摘要
本文报道48例骨髓增生异常综合征(MDS)的临床和血液学表现,其中13例经近3年发展成急性白血病。讨论了MDS 的细胞形态学和细胞化学改变的诊断及预后意义。提出了难治性贫血与红血病相鉴别的初步标准。
This paper presents forty-eight cases with myelodysplastic Syndrome (MDS).
The importance of cytomorphology and cytochemistry for diagnosis are emphasized.
Thirteen patients had transformed into acute leukemia most of which are ANLL after following up for three years.The following laboratory findings appear to be of diag-
nostic and prognostic importance;nuclear abnormalities of erythroblasts,small mye-
loblast,Auer's bodies,promonocytoid cell,micromegakaryocyte,erythroid cell strongly
positive on PAS stain,atypical ring sideroblast(less than 15%) and decrease of NAP
activity.We recommend the following standard to distingwish erythremia from RA:
1.erythoid cells more than 600% in bone marrow,2.more than 10% of erythroid cells
have nuclear abnormalities,3.erythroid cells are strongly positive(?)on PAS stain.
出处
《苏州医学院学报》
1990年第1期33-36,83-84,共4页
Acta Academiae Medicinae Suzhou
关键词
骨髓增生异常
细胞形态
细胞化学
myelodysplastic syndrome
cytomorphology
cytochemistry
