摘要
目的:探讨男性老年骨质疏松症患者血清IL-8、降钙素(CT)、骨钙素(BGP)和睾酮(T)含量的变化及临床意义。方法:应用放射免疫分析对33例男性老年骨质疏松症患者进行了血清IL-8、CT、BGP和T检测,并与35名正常人组作比较。结果:男性老年骨质疏松症患者血清IL-8水平非常显著地高于正常人组(P<0.01),而CT、BGP、T水平则显著地低于正常人组(P<0.01),且血清IL-8水平与CT、BGP、T水平呈明显负相关(r=-0.4712、-0.5014、-0.4915,P<0.05)。结论:检测男性骨质疏松症患者血清IL-8、CT、BGP和T水平为临床的诊断和治疗提供了有价值的数据。
Objective To study the clinical significance of changes of serum contents of IL-8 calcitonin （CT） bone glaprotein （BGF） and testosterone （T） in elderly men widtosteoporosis. Methods The serum IL-8, CT, BCP and T levels were determined with RIA in 33 elderly men with osteoporosis and 35 controls. Results The serum levels of IL-8 were significandy higher, but levels of CT, BGP and T were significantly lower in the elderly men with osteoporosis than those in controls （P 〈 0.01 ）. There were significandy negative relationship between the serum levels of IL-8 and serum levels of CT, BGP and T （ r = - 0. 4712, - 0. 5014, - 0.4915, P 〈 0.05）. Conclusion The changes of IL-8, CT, BGP and T levels correcdy reflected increase of bone absorption with less osteogenesis, which was characteristic in osteoporosis.
出处
《放射免疫学杂志》
CAS
2011年第1期13-15,共3页
Journal of Radioimmanology
关键词
男性老年骨质疏松症
白细胞介素-8
降钙素
骨钙素
睾酮
elderly men osteoporosis, interleukin-8 （IL-8）, calcitonin （CT）, bone glaprotein （BGP）, testosterone （T）
