摘要
组织工程化骨和软骨组织已初步用于临床修复骨和软骨缺损,显示了临床应用前景。在周围神经的组织工程研究中,已建立了MSC 800永生雪旺细胞系。用多孔、中空纤维管复合多种细胞外基质和雪旺细胞,有显著促进神经再生作用。用不同来源的成骨细胞与不同组成成分和结构的支架复合,在体内和体外都观察到成骨现象。在动态压力下培养软骨细胞,与高分子支架材料复合培养形成的软骨组织具有更好的形态和功能。
Tissue engineered bone and cartilage have been applied in clinic repairing bone and cartilage defect, and it has good prospect in clinic application, hi the tissue engineering of peripheral nerve, it has been established MSC 800 Schwann' s infinite cell line. It can be significantly promote nerve regeneration used porous hollow fiber tube composite with various extracellular matrix and Schwann s cells. Osteogenesis can be observed in vitro and in vivo used osteoblast of different sources composite with scaffold materials of different component and structure. It has better morphosis and function of cartilage tissues which come from chondrocyte cultured in dynamic pressure and composited with macromolecu-lar materials.
出处
《中国科学基金》
CSCD
1999年第4期212-216,共5页
Bulletin of National Natural Science Foundation of China
基金
国家自然科学基金
批准号39830100
