摘要
目的评价1448例急性ST段抬高性心肌梗死(STEMI)患者的抗栓治疗现状。方法回顾性分析2006年至2008年在宁夏地区不同级别医院收治的STEMI患者的临床资料。结果三级医院药物使用率:阿司匹林98.7%,氯吡格雷97.3%,肝素96.4%;二级医院药物使用率:阿司匹林89.4%,氯吡格雷32.1%,肝素84.6%。三级医院药物联合使用率:两联96.2%,三联93.7%;二级医院分别为31.3%,28.8%。介入组药物使用率:阿司匹林99.4%,氯吡格雷99.8%,肝素99.1%;非介入组药物使用率:阿司匹林93.1%,氯吡格雷58.9%,肝素88.3%。介入治疗组药物使用率显著高于非介入治疗组。结论我区近年来三甲医院的抗栓药物使用率略优于国内外大型临床试验结果,二级医院药物使用率略低于国内水平。需要进一步提高我区二级医院的指南贯彻力度。
Objective To evaluate current status of antithrombotic therapy in 1448 patients with STEMI in the Ningxia province. Methods Retrospectively analysed the patients＇ clinical records of different administrative levels of hospitals with final diagnosis of STEMI from 2006 to 2008 in Ningxia. Results 1.Percentage of medication coverage in tertiary hospitals were aspirin 98.7%,clopidogrel 97.3%,heparin 96.4% and in secondary hospital aspirin 89.4%,clopidegrel 32.1%,and heparin 84.6% respectively. The coverage rate in tertiary hospitals was higher than in secondary hospitals （P0.01）.2. The percentage of combination therapy in tertiary hospitals were combination of two drugs：96.2% and combination of three drugs：93.7%. The percentages were 31.3% and 28.8% in the secondary hospitals respectively. The percentage of patients receving combination therapy was higher in tertiary hospitals （P0.01）.3. Percentage of medication used in patients underwent PCI included aspirin 99.4%,clopidogrel 99.8%,heparin 99.1% and the percentage was 93.1%,58.9% and 88.3% in patients without PCI respectively. Conclusion The coverage of antithrombotic therapy in tertiary hospitals is satisfactory and comparable with results from other clinical study.The percentage of medication coverage is lower in secondary hospitals. Antithrombotic therapy according to guidelines recommendation should be emphasized more in secondary hospitals.
出处
《中国介入心脏病学杂志》
2010年第6期306-308,共3页
Chinese Journal of Interventional Cardiology
基金
2009年度宁夏高等学校科学研究项目(2009JY006)
关键词
心肌梗死
纤维蛋白溶解药
回顾性研究
Myocardial infarction
Antithrombotic agents
Retrospective studies
