摘要
目的：研究 Ｉ Ｃ Ａ Ｍ １ 表达与膀胱癌生物学行为的关系。方法：应用免疫组化法对 ４０ 例石蜡包埋的膀胱癌标本中 Ｉ Ｃ Ａ Ｍ １ 表达进行检测。结果：膀胱癌组织中 Ｉ Ｃ Ａ Ｍ １ 表达阳性率为８８％ ，而安全缘组织中阳性率为 １６％ ，两者之间差异非常显著，且 Ｉ Ｃ Ａ Ｍ １ 的表达与膀胱癌的临床分期与病理分级呈负相关，即随膀胱癌的临床分期和病理分级的增高 Ｉ Ｃ Ａ Ｍ １ 表达降低。结论：膀胱癌组织 Ｉ Ｃ Ａ Ｍ １ 表达检测可以作判定患者机体免疫功能状态、治疗效果及预后观察的客观指标。
Objective:To study the relation between ICAM 1 expression and biological action of bladder carcinoma.Methods:ICAM 1 expression in 490 samples of bladder carciroma imbedded by paraffin were determined by immunohistochemical method.Results:Positive rate of ICAM expression in bladder carcinoma tissue was 88% and positive rate of safety limbs was 16%.Difference between them was significant.ICAM 1 expression was negatively correlatal with clinical stages and pathological grading.Conclusion:We can use the examination of ICAM 1 in bladder carcinoma tissue as index in judging immunological function state,therapeutic effect and prognosis.
出处
《白求恩医科大学学报》
CSCD
1999年第5期624-625,共2页
Journal of Norman Bethune University of Medical Science
