期刊文献+

自主神经系统在阵发性心房颤动发作前后心率变异性变化中的作用 被引量:3

The Changes of Heart Rate Variability Before and After Paroxysmal Atrial Fibrillation
暂未订购
导出
摘要 目的分析阵发性心房颤动发作前后心率变异性的变化,探讨自主神经系统在阵发性心房颤动中的作用。方法采用动态心电图记录28例阵发性心房颤动患者24h心电信息,分析其发作前后5min及白天(6:00~22:00)和夜间(22:00~6:00)的心率变异性指标。结果心房颤动发作前5min平均正常R—R间期的标准差(SDNN)、高频成份(HF)较终止后5min显著升高(P〈0.01),低频/高频比值(LF/HF)显著降低(P〈0.01),LF无变化:LF、HF白天均高于夜间(P〈0.01),白天与夜间SDNN、LF/HF无差异;阵发性心房颤动发作前5minSDNN与阵发性心房颤动发作频率呈正相关(r=0.545。P〈0.01),LF/HF与阵发性心房颤动发作频率和持续时间呈负相关(r=-0532、-0.563,均P〈0.01)。结论阵发性心房颤动发作前心率变异性升高,迷走神经支配占优势,使心房颤动得以诱发和持续。 Objective To analyze heart rate variability(HRV) before and after paroxysmal atrial fibrillation(AF) and effect of autonomic nervous system on paroxysmal AF. Methods The parameters of HRV in a five-minute period just before and immediately after paroxysmal AF and those during day and night were analyzed on 24-hour dynamic electrocardiogram recordings in 28 patients with paroxysmal AF. Results The standard deviation of normal-to-normal intervals (SDNN) and high-frequency (HF) power in a five-minute period were significantly higher before than after paroxysmal AF (P〈0.01), while low-frequency (LF) power was unchanged. LF / HF ratio was significantly lower before paroxysmal AF (P〈0.01). SDNN in a five-minute period before paroxysmal AF was positively correlated with frequency of paroxysmal AF (r=0.545, P〈0.01), while LF/HF negatively correlated with frequency and duration of paroxysmal AF (r=-0.532, -0.563, P〈0.01). Conclusion Increased HRV may contribute to initiation and maintenance of paroxysmal AF.
出处 《心电学杂志》 2011年第1期8-10,共3页 Journal of Electrocardiology(China)
关键词 动态心电图 阵发性心房颤动 心率变异性 自主神经系统 Dynamic electrocardiogram Paroxysmal atrial fibrillation Heart rate variability Autonomic nervous system
  • 相关文献

参考文献10

  • 1Hassaguerre M,Jais P,Shab D C,et al.Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins.N Engl J Med,1998,339:659-666.
  • 2Chen S A,Hsieh M H,Tai C T,et al.Initiation of atrial fibrillation by ectopic beats originatingfrom the pulmonary veins:electrophysio-logical characteristics,pharmacological responses,and effects of radio frequency ablation.Circulation,1999,100:1879-1886.
  • 3Schauerte P,Scherlag B J,Patterson E,et al.Focal atrial fibrillation:experimental evidence for a pathophysiologic role of the autonomic nervous system.J Cardiovasc Electrophysiol,2001,12:592-599.
  • 4Zimmermann M,Kalusche D.Fluctuation in autonomic tone is a major determinant of sustained atrial arrhythmias in patients with focal ectopy originating from the pulmonary veinsJ Cardiovasc Electrophysiol,2001,12:285-291.
  • 5Valentin F,Larse R,Richard W,et aI.ACC/AHA/ESC Guideline for the management of patients with artial fibrillation:Creative Summary.J Am Coll Cardiol,2001,38:1231-1265.
  • 6Kleiger R E,Stein P K,Bosner M S,et al.Time domain measurements of heart rate variability.Cardiol C1in,1992,10:487.
  • 7Olshansky B.Interrelationships between the autonomic nervous system and atrial fibrillation.Prog Cardiovasc Dis,2005,48:57-78.
  • 8Lombardi F.Heart rate variability-macrohythm and microrhythm.In:Deegen T and San PI eds.Time Structure and Heart.New York:Oxford University Press,1998:751-767.
  • 9Bosch R F,Scherer C R,Rub N,et al.Molecular mechanisms of early electrical remodeling:transcriptional down-regulation of ion channel subunits reduces I (Ca,L) and I (to) in rapid atrial pacing in rabbits.J Am Coll Cardiol,2003,41:858-869.
  • 10Ehrlich J R,Zicha S,Coutu P,et al.Atrial fibrillation-associated minK38 G/S polymorphism modulates delayed rectifiercurrent and membrane localization.Cardiovasc Res,2005,67:520-528.

同被引文献23

引证文献3

二级引证文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部