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滋阴清热法对咳嗽变异性哮喘患者疗效及ECP、IL-5的影响 被引量:5

Effect of Ziyinqingre Therapy on Clinical Efficacy,ECP and IL-5 in Patients with Cough Variant Asthma
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摘要 目的观察滋阴清热法治疗咳嗽变异性哮喘(CVA)的临床疗效及对血清嗜酸粒细胞阳离子蛋白(ECP)、白细胞介素-5(IL-5)水平的影响。方法选择2009年4月-2010年1月解放军总医院门诊符合诊断标准的CVA患者70例随机分为两组,治疗组给予滋阴清热法为主组方的汤剂,对照组给予茶碱缓释胶囊治疗;两组均以4周为1个疗程。分别在治疗前后观察患者咳嗽、咽痒、咯痰、气急等症状积分情况,检测患者血清ECP、IL-5的含量。结果治疗组患者症状改善优于对照组,其ECP、IL-5水平下降程度较对照组明显。结论滋阴清热法治疗CVA,可降低患者血清ECP、IL-5水平,从而减轻症状。 Objective:To observe the effect of Ziyinqingre Therapy on clinical efficacy,ECP and IL-5 in patients with cough variant asthma(CVA).Methods:70 CVA patients were randomly divided into the control group and the treatment group.The treatment group was treated with the Ziyinqingre Therapy.The control group was used the theophylline sustained-release capsules.After a treatment course for 4 weeks,the cough,the throat itching,the expectoration and the breath shortness were observed in 2 groups.Meanwhile,the ECP and the IL-5 were detected in the 2 groups.Results:These symptom improvments of the treatment group were superior to those of the control group.These declines of the ECP and the IL-5 in the treatment group were more obvious than those in the control group.Conclusion:The Ziyinqingre Therapy could treat the CVA.It could decrease the ECP and the IL-5 to relieve the clinical symptoms.
出处 《中国中医急症》 2011年第2期199-201,共3页 Journal of Emergency in Traditional Chinese Medicine
关键词 咳嗽变异性哮喘 嗜酸粒细胞阳离子蛋白 白细胞介素-5 滋阴清热法 Cough variant asthma Eosinophil cationic protein IL-5 Ziyinqingre Therapy
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