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养心合剂对慢性心力衰竭患者血浆NT-proBNP和心率变异性的影响 被引量:3

Observation of Yangxinheji on the treatment of myocardial failure
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摘要 目的:观察养心合剂佐治慢性充血性心力衰竭的临床疗效。方法:慢性心衰患者70例随机分为对照组31例和治疗组39例。对照组常规治疗,治疗组加用养心合剂,8周为1个疗程。观察心功能、血浆Nt-proBNP和心率变异性的改变。结果:治疗组治疗后心功能明显改善,血浆Nt-proBNP明显下降,心率变异性参数中SDNN、SDANN、SDNN I均明显升高,治疗前后比较有统计学意义(P<0.01或P<0.05);其中心功能及SDNN、SDANN、SDNN I两组比较差异也有统计学意义(P<0.01或P<0.05)。结论:养心合剂佐治慢性心衰,可进一步改善心功能,改善预后。 Objective:To observe the effect of Yangxinheji on the treatment of myocardial failure.Methods:70 patients with myocardial failure were randomly divided into twogroups.Patients in controlgroup(n=31) were treated with routine therapy.Patients in treatmentgroup(n=39) were treated with Yangxinheji additionally.The therapeutic course was 8 weeks.Heart function,changes of Nt-proBNP and heart rate variability were observed.Results:After treatment,for the treatmentgrout,heart function was improved,Nt-proBNP level decreased,SDNN,SDANN and SDNN I increased(P〈0.01 or P〈0.05).For the heart function,SDNN,SDANN and SDNN I,there were significant differences between the twogroups(P〈0.01 or P〈0.05).Conclusion:Combination of Yangxinheji and routine therapy has agood effect on myocardial failure.
机构地区 陕西省中医院
出处 《辽宁中医杂志》 CAS 北大核心 2011年第2期292-293,共2页 Liaoning Journal of Traditional Chinese Medicine
基金 陕西省中医管理局资助项目(2007-57)
关键词 养心合剂 充血性心力衰竭 心功能 NT—proBNP 心率变异性 Yangxinheji; Myocardial failure; Heart function; NT-proBNP; Heart rate variability;
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