摘要
目的：探讨降低胆道感染病人血清总胆汁酸值，减少胆汁酸的急、慢性毒性作用的方法。方法：根据中医学“六腑以通为用”学说，采用疏肝利胆、清热通下法治疗１０７例胆道感染病人，同时进行ＡＰＡＣＨＥ－Ⅱ评分和血清总胆汁酸值测定，与６４例常规西医治疗病人比较分析。结果：１中西医结合非手术治疗组和手术治疗组的血清总胆汁酸值降低幅度大，降低速度快，与对应的常规西医治疗组相比有显著差异（Ｐ＜００５）。２经治疗后４组的ＡＰＡＣＨＥ－Ⅱ评分均随总胆汁酸值下降而显著降低（Ｐ＜００５）。３中西医结合治疗组并发症的发生率较常规西医治疗组显著降低（Ｐ＜００５）。结论：１中西医结合治疗能有效地降低血清总胆汁酸，减轻胆汁酸的急、慢性毒性作用，减少并发症发生率。２再次证实血清总胆汁酸值对外科疾病严重程度的评估价值。
Objective:To study the TCM therapy for reduction of the
total bile acid (TBA)level in biliary tract infection patients and the acute and chronic
toxicity of TBA.Methods:One hundred and seven patients with acute bilary tract infection
were treated with TCM therapy of “Shu Gan Li Dan and Qing Re Tong Xia”
supplemented to routine western medicine as treatment group,while their APACHE Ⅱ
scores were evaluated and their TBA levels were measured,compared with 64 cases
treated with western medicine alone as control group.Results:(1)Serum TBA of patients in
the treatment group was significantly reduced more rapidly and in greater extent
compared with that in control group.(2)The APACHE Ⅱscore of patient in the treatment
group were all significantly reduced with the reduction of TBA level.(3)The morbidity in
the treatment group was significantly lower than that in the control ( P<0 05
).Conclusion:(1)Integrated traditional Chinese and western medicine was valuable in
reduction of the level of TBA and acute and chronic toxic effects,and of morbidity.(2)The
predictive value of serum TBA value in the evaluation of the severity and prognosis of
surgical diseases was further confirmed.
出处
《中国中西医结合外科杂志》
CAS
1999年第4期199-202,共4页
Chinese Journal of Surgery of Integrated Traditional and Western Medicine
关键词
疏肝利胆
清热通下法
急性
胆道感染
TCM therapy,acute biliary tract
infection,TBA,toxicity
