摘要
目的：通过７７例老年人胸腔积液（简称胸液）ＡＤＡ、ＬＺＭ、ＬＤＨ活性的联合检测，为老年性胸液的定性诊断提供一种快速、简便、有效的方法．方法：７７例老年人胸液分为三组：结核组：２６例；肿瘤组：３９例；漏出液组：１２例。常规抽胸液，分别用改良的Ｍａｒｔｉｍｋ酚钠试剂氨直接比色法、单向琼脂扩散法、２，４—二硝基苯肼法检测血清、胸液中ＡＤＡ、ＬＺＭ、ＬＤＨ。结果：结核性胸液中ＡＤＡ、ＬＺＭ活性明显高于肿瘤组和漏出液组（Ｐ＜０．０１）。胸液中ＡＤＡ、ＬＺＭ、与血清中ＡＤＡ、ＬＺＭ的比值，结核组均有９２．３％大于１．０，而肿瘤组分别为７．７％和１５．４％；漏出液组两者均小于１．０。结核性、肿瘤性胸液中ＬＤＨ活性明显高于漏出液组（Ｐ＜０．０１），而结核组与肿瘤组间无差异（Ｐ＞０．０５）。结核组与肿瘤组胸液ＬＤＨ与血清ＬＤＨ的比值均大于０．６，而漏出液组均小于０．６。结论：老年人结核性胸液ＬＤＨ、ＡＤＡ与血汪ＬＤＨ、ＬＺＭ均升高，而肿瘤性胸液表现为ＬＤＨ升高、ＡＤＡ、ＬＺＭ降低，漏出性胸液表现为ＬＤＨ、ＡＤＡ、ＬＺＭ均降低。联合检测胸液中的三种酶对老年结核性胸液的诊断率为７３．１％，特异性为１００％；对肿瘤性胸液诊断率为７?
Objective: Toexploreanewmethodwhichisquick,easyandeffectiveforthediagnosisofsenilitypleuraleffusion. Methods: TheactivityofADALZMLDHwerecombineddetectedin77cases.Allofthemweredividedintothreegroups:Tuberculosisgroup:26cases;Tumorgroup39cases;Transudategroup:12cases.TowithdrawlpleuraleffusionnormallyandthendetectbloodserumandADALZMLDHinpleuraleffusionbyimprovingMartimkphenolsodiumreagentammoniacolorimetrydirectlysimpleagardiffusiontestand2,4-dinitrophenylhydrazineseparately.5,5HZResults: TheactivityofADALZMintuberculosisgroupismorethan thoseintumorandtransudategroup(P<0.01);TheLDHratioofpleuraleffusionandbloodserumismorethan0.6intuberculosisandtumorgroup.whiletheratioislessthan0.6intransudategroup. Conclusions: TheLDHADALZMallincreasedinsenilitypleuraleffusionpatients.However,theLDHincreased,ADALZMdecreasedintumorgroup;LDHADALZMalldecreasedintransudategroup Throughcombineddetectionofthethreekindsofenzyme,Thediagnosisrateis73.1%79.5%100%andthespecificityis100%93.9%100%intuberculosisgrouptumorgroupa
出处
《河北医学》
CAS
1999年第7期6-9,共4页
Hebei Medicine
