摘要
目的:探讨经导管肝动脉化疗栓塞术与部分性脾动脉栓塞术(PSE)联合治疗对原发性肝癌合并脾功能亢进患者的血象及肝功能的影响。方法:原发性肝癌合并脾亢32例,采用经皮穿刺肝动脉化疗栓塞术(TACE)联合部分性脾动脉栓塞术(PSE)治疗,治疗前后测定血细胞数量。结果:双介入术后24h、1周、4周血白细胞和血小板均较栓塞前明显升高(P<0.01),术前与术后比较患者的TBIL、ALT及Child-Pugh评分比较,差异均有统计学意义(P<0.05)。结论:双介入治疗是治疗肝癌合并肝硬化脾功能亢进安全、有效的方法。
Objective To study the effect and method of transcatheter hepatic arterial chemoembolization（TACE） combined with partial splenic embolization（PSE） for treatment of liver cancer with portal hypertension and hypersplenism.Methods TACE combined with PSE was performed in 32 patiens with hepatocellular carcinoma complicated with portal hypertension and hypersplenism.The blood cell count and hepatic function were examined both before and after embolization.Results Comparised with pre-embolization a significant increase in the peripheral leukocyte and platelet count was found from 24 hours,1 week and 4 weeks after the embolization.Remarkable change in the levels of TBIL,ALTand Child Pugh scores after therapy was shown at 24 hours,1week and 4 weeks later（P0.05）.Conclusion TACE combined with PSE is a safe and effective procedure for patients with hepatocellular carcinoma associated with liver cirrhosis,portal hypertension and hypersplenism.
出处
《吉林医学》
CAS
2011年第3期427-428,共2页
Jilin Medical Journal
关键词
原发性肝癌
脾功能亢进
双介入治疗
Hepatocellular carcinoma
Hypersplenism
Interventional therapy
