摘要
目的:探讨胸腔积液C反应蛋白(CRP)、乳酸脱氢酶(LDH)测定及胸水/血CRP、胸水/血LDH在鉴别结核性和恶性胸腔积液中的临床意义。方法:采用速率散射比浊法,用日立7170全自动生化分析仪同时测定47例结核性和25例恶性胸腔积液病人的胸水及血的CRP浓度和LDH水平。结果:结核性胸液CRP水平明显高于恶性胸液CRP值(分别为(14.24±7.53)mg/L与(7.70±1.46)mg/L,P<0.05),结核性及恶性胸液胸水/血CRP浓度比值比较差异无显著性(P>0.05),结核性胸液及恶性胸液LDH及胸水/血LDH比值比较差异均无显著性(P>0.05)。结论:CRP浓度测定是临床上常用的快速、实用、简易的检测方法,对鉴别结核性和恶性胸积液具有较大的临床诊断价值。
Objective：To investigate the application value of C-reactive protein（CRP） and lactate dehydrogenase（LDH）,pleural effusion CRP/ serum CRP and pleural effusion LDH/serum LDH in differentiating tuberculous and malignant pleural effusions.Methods：The rate nephelometry was adopted by Hitachi 7170 automatic biochemical analyzer to simultaneously detect CRP and LDH in serum and pleural effusion in 47 cases of tuberculous and 25 cases of malignant pleural effusions.Results：The CRP level of tuberculous effusion was obviously higher than that of malignant effusion[（14.24±7.53）mg/L vs.（7.70±1.46） mg/L,P0.05].The ratio of tuberculous and malignant effusions CRP and serum CRP had unsignificant difference（P0.05）.LDH in tuberculous and malignant effusions,and the ratio of tuberculous and malignant effusions LDH with serum LDH all had unsignificant difference（P0.05）.Conclusion：The detection of CRP level is a usual,rapid,practical and simple detecting method,which has larger value to differentiating tuberculous and malignant effusions.
出处
《现代医药卫生》
2011年第1期18-20,共3页
Journal of Modern Medicine & Health
