摘要
对４５例原发性高血压病尸检资料进行回顾性研究。重点观察了全身细动脉的改变，将直径＜１００μｍ者称远端细动脉，而１００～３００μｍ者称为近端细动脉。结果：所观察到的病变可分为：管壁血浆蛋白浸润及透明变性两类，后者又视其严重程度分为Ⅰ、Ⅱ、Ⅲ级。并有如下发现：①身体不同区域的细动脉处于不同改变程期；②远端细动脉改变在先，近端细动脉改变在后，而脑近端细动脉先发生扩张，相继才发生透明变性；③腹腔内各器官细动脉改变发生较早，尤以肾最早，而脑改变较迟，心、肺细动脉改变很轻或无改变；④同一器官不同部位细动脉的改变先后不一；⑤不同器官细动脉硬化构成的后果不一样。作者并探讨了原发性高血压病细动脉硬化的机理。
The autopsy mateials of 45 cases of primary hypertension were studied retrospectively. The arteriolar lesions were reviewed. The arterioles <100 m in diameter were defined as distal arterioles; those 100 m and <300 m in diameter were proximal arterioles. The lesions of arteriolar wall were categorized as plasma infiltration and hyaline degeneration, and according to seriousness, the latter was divided into three degrees: , and .The results revealed that (1) the arteriolar lesions in different areas of the body were at different stages of seriousness; (2) the changes in the distal arterioles were earlier than those in the proximal ones; in brain, the proximal arterioles dilated first, and then occurred the hyline degeneration;(3) hyaline degeneration took place early in the abdominal organs such as kidney, liver and pancreas, but relatively late in brain; (4) different parts of an organ were at different stages of seriousness; and (5) the lesions in different organs led to different consequences. Th e pathogenesis of arteriolar sclerosis in primary hypertension was also discussed.
出处
《华西医科大学学报》
CSCD
1999年第2期188-191,共4页
Journal of West China University of Medical Sciences
关键词
高血压
细动脉
透明变性
尸检
Primary hypertensionArterioleHyaline degeneration
