摘要
目的 :探讨多巴酚丁胺 (DOB)负荷 2 0 1Tl心肌单光子发射计算机断层显像对冠状动脉病变的诊断价值。方法 :对 70例临床确诊或疑诊冠心病的患者在冠状动脉造影前后 2周内进行 DOB负荷 2 0 1Tl心肌断层显像。结果 :DOB2 0 1Tl心肌断层显像诊断冠心病的敏感性为 93.3% ,特异性为80 .0 % ;单、双、三支冠状动脉受累时的敏感性为 90 .9%、93.7%、10 0 % ;心肌显像对左前降支、回旋支和右冠状动脉病变诊断的敏感性和特异性分别为 6 8.5%、75.0 % ,4 2 .9%、97.6 %和 81.6 % ,87.5%。负荷试验终点时双支、三支血管病变 DOB用量明显低于单支病变用量 (P <0 .0 1)。试验中未见严重不良反应。结论 :DOB2 0
Objective:To evaluate the clinical value of dobutamine stress2 0 1Tl myocardial SPECT in detecting coronary artery disease.Method:70 patients with defined or suspected coronary artery disease were performed dobutamine stress2 0 1Tl myocardial SPECT within two weeks of coronary angiography. Result:2 0 1Tl myocardial SPECT imaging identified coronary disease with a sensitivity of93.3% ,specificity of80 .0 % ;one、two and three- vessel disease with a sensitivity of90 .9% , 93.7% and10 0 % ,respectively.The sensitivity and specificity of2 0 1Tl myocardial SPECT was 6 8.5% ,75.0 % for detecting L AD lesion,4 2 .9% ,97.6 % for LCX lesion and 81.6 % ,87.5% for RCA lesions,respectively.The dobutamine ischemic threshold was significantly lower in patients with two- vessel and three- vessel disease than in patients with one- vessel disease.No serious side effects occured.Conclusion:Dobutamine stress2 0 1Tl myocardial SPECT imaging seems to be safe and has high value in detecting coronary arteries disease.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
1999年第5期227-229,共3页
Journal of Clinical Cardiology
