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阿司匹林心血管病一级预防新证据 被引量：10

New evidence of Aspirin for primary prevention of cardiovascular disease
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摘要 本文详细介绍了阿司匹林在心血管疾病一级预防的新证据:高血压最佳治疗研究(HOT)的肾功能异常亚组分析和澳大利亚Fremantle糖尿病研究,并对美国3个学会的声明进行评述,认为这些最新的证据进一步证实了阿司匹林的一级预防效益。 Summary ： This paper describes the new evidence of aspirin for primary prevention of cardiovascular disease ： subgroup analysis of hypertensive patients with renal dysfunction in HOT study and Australia Fremantle Diabetes Study. The statements of ADA,AHA and ACCF were reviewed,and the latest evidences further confirmed the effectiveness of primary prevention of aspirin.
作者 施仲伟
机构地区 上海交通大学医学院附属瑞金医院心脏科
出处 《中国实用内科杂志》 CAS CSCD 北大核心 2011年第2期152-154,共3页 Chinese Journal of Practical Internal Medicine
关键词 阿司匹林 心血管疾病 一级预防 aspirin cardiovascular disease primary prevention
分类号 R5 [医药卫生—内科学]
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参考文献9

  • 1U. S. Preventive Services Task Force. Aspirin for the prevention of cardiovascular disease:U. S. Preventive Services Task Force Rec- ommendation Statement [ J ]. Ann Intern Med, 2009, 150 ( 6 ) : 396 - 404.
  • 2Hansson L, Zanchetti A, Carruthers S, et al. Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hy- pertension:principal results of the Hypertension Optimal Treatment (HOT) randomised trial[J]. Lancet, 1998,351 (9118) :1755 - 1762.
  • 3Jardine M J, Ninomiya T, Perkovic V, et al. Aspirin is bene? cial in hypertensive patients with chronic kidney disease. A post-hoc sub- group analysis of a randomized controlled trial [ J ]. J Am Coll Car- diol,2010,56(12) :956 -965.
  • 4Berger AK, Duval S, Krumholz HM. Aspirin, beta-blocker, and an- giotensin-eonverting enzyme inhibitor therapy in patients with end- stage renal disease and an acute myocardial infarction [ J ]. J Am Coll Cardiol, 2003,42 ( 2 ) :201 - 208.
  • 5Ong G, Davis TM, Davis WA. Aspirin is associated with reduced cardiovascular and all-cause mortality in type 2 diabetes in a pri- mary prevention setting [ J ]. Diabetes Care, 2010,33 ( 2 ) : 317 - 321.
  • 6Belch J, MacCuish A, Campbell I, et al. The prevention of progres- sion of arterial disease and diabetes (POPADAD) trial: factorial randomised placebo controlled trial of aspirin and antioxidants in patients with diabetes and asymptomatic peripheral arterial disease [ J]. BMJ,2008,337 :a1840.
  • 7Ogawa H, Nakayama M, Morimoto T,et al. Low-dose aspirin for primary prevention of atherosclerotic events in patients with type 2 diabetes : a randomized controlled trial [ J ]. JAMA, 2008, 300 (18) :2134 -2141.
  • 8Wood RL, Tonkin AM, Nelson MR, et al. Should aspirin be used for the primary prevention of cardiovascular disease in people with diabetes? [J]. Med J Aust,2009,190( 11 ) :614 -615.
  • 9Pignone M, Alberts M J, ColweU JA, et al. Aspirin for primary pre- vention of cardiovascular events in people with diabetes :a position statement of the American Diabetes Association, a scientific state- ment of the American Heart Association, and an expert consensus document of the American College of Cardiology Foundation [ J ]. Circulation,2010,121 ( 24 ) : 2694 - 2701.

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中国实用内科杂志
2011年 第2期

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