摘要
血管内皮细胞(ECs)功能众多,易受到血管内的危险因素作用,造成血管内皮功能障碍(ED),目前检测ED的手段仍存在局限性。原子力显微镜(AFM)可在纳米级提供关于细胞表面形态及机械性能的信息,可作为研究ED的新手段。该文对利用AFM研究ED最新进展进行综述。
Endothelial cells(ECs) with a variety of functions are vulnerable to attack by various risk factors.These risk factors of vascular pathology lead to endothelial dysfunction(ED).However,the present methods of evaluating ED have their limitations.Atomic force microscope(AFM),which can offer the information on the surface images and the mechanical properties of the single cell at nanometer scale,will become a new technical approach to ED evaluation.This review focuses on the recent progress in the application of AFM to assess ED.
出处
《生物医学工程学杂志》
EI
CAS
CSCD
北大核心
2011年第1期184-188,共5页
Journal of Biomedical Engineering
关键词
血管内皮细胞
血管内皮功能障碍
原子力显微镜
Endothelial cells(ECs)
Endothelial dysfunction (ED)
Atomic force microscope(AFM)