摘要
FTZ-F1基因属于孤核受体超家族成员,最初是在果蝇(Drosophila)中发现的,该基因在果蝇胚胎发生的早期调控体节分化基因ftshi-tarazu(FTZ)表达。目前已经发现了很多它的同源基因。研究证明它在类固醇生成、性别分化过程中都发挥着重要的作用。鱼类在脊椎动物系统进化中处于承前启后的地位,是脊椎动物中分布最广、种类最多的类群,具有多种多样的生物学特征和重大的经济价值,所以对于鱼类性别决定机理的研究具有重大意义。文章就鱼类中发现的性别相关基因FTZ-F1,及该基因在胚胎发育过程中的作用、在性逆转鱼中的作用及与芳香化酶的相互作用关系等进行了综述,旨在为系统研究鱼类性别决定机制提供参考。
The fushi tarazu factor-1（FTZ-F1） is a member of the nuclear receptor superfamily and originally found as a regulator of the Drosophila homeobox segmentation gene FTZ.Identified its homologs in many species play important roles in both steriodogenesis and sexual differentiation.Fish species are in special position in the evolution of vertebrate,and are the most distributed and varied species in vertebrates,and possess various biological characteristics and have great economic value.It is,therefore,significant to conduct the studies on the sex-determining mechanism of fishes.This paper mainly presented the research progress of sex related gene FTZ-F1 of fishes,the function during the embryonic development and sex reversal of fish,and the interaction between FTZ-F1 and the aromatase,which are helpful for studying the mechanism of sex determination in fish.
出处
《水产学杂志》
CAS
2010年第4期54-59,共6页
Chinese Journal of Fisheries
基金
山西省自然科学基金项目(2009021038)
山西农业大学科研启动基金(XB2009003)
山西农业大学科技创新基金(2009005)
广西自治区直属公益性科研院所基本科研业务费专项资金项目(2060302GXIF-2008-01)
南宁市科学研究与技术开发计划项目(200801016B)
