摘要
目的分析皮下注射奥曲肽对预防胰十二指肠切除术后腹内并发症的预防效果。方法回顾性分析2003年1月至2008年12月间施行的68例胰十二指肠切除术患者的临床资料，其中对照组31例，奥曲肽治疗组（奥曲肽组）37例。从手术后当日至术后5d奥曲肽组每天3次皮下注射奥曲肽，每次0．1mg，观察胰漏、腹腔并发症发生率。结果奥曲肽组腹内并发症发生率显著低于对照组，差异有统计学意义（P〈0．05）；胰漏发生率低于对照组，但差异无统计学意义（P〉0．05）。结论经皮下注射奥曲肽能显著降低胰十二指肠切除术后腹内并发症发生率。
Objective To examine the effect of subcutaneous injection of octreotide in the prevention of intra - abdominal complications after pancreatoduodenectomy. Methods The clinical data of 68 cases of pancreatoduodenectomy performed from January 2003 to December 2008 were retrospectively analyzed. Thirty - one cases in the control group were not injected with octreotide. In the octreotide group, 37 patients were subcutaneously injected with octreotide 0.1 mg three times daily from post - operative day 0 to day 5. The intra - abdominal complications and pancreatic fistulas were observed. Results The in- cidence of intra - abdominal complications and pancreatic fistulas were significantly lower in the octreotide group than those in the control group with differences being significant （P 〈 0.05 for each）. Conclusion Subcutaneous injection of octreotide can significantly reduce the incidence of intra - abdominal complications after pancreatoduodenectomy
出处
《临床外科杂志》
2010年第6期384-385,共2页
Journal of Clinical Surgery
关键词
胰十二指肠切除术
奥曲肽
术后并发症
胰漏
pancreatoduodenectomy
octreotide
postoperative complications
pancreatic fistula
