摘要
目的:探讨慢性阻塞性肺疾病患者营养状况与T淋巴细胞亚群(CD3+、CD4+、CD8+、CD4+/CD8+)分布的关系。方法:将慢性阻塞性肺疾病患者38例,对其进行T淋巴细胞亚群测定;根据患者身高、体重及白蛋白,将其分为营养正常与营养不良2组,分析患者营养状况与T淋巴细胞亚群分布的关系。结果:营养不良组CD3+、CD4+、CD4+/CD8+比值明显低于营养正常组(P<0.01),而CD8+无明显变化(P>0.05)。结论:慢性阻塞性肺疾病患者营养不良影响T淋巴细胞亚群的分布,导致机体免疫功能下降。
Objective：To investigate the relationship between nutritional status and T lymphocyte subsets（CD3＋,CD4＋,CD8＋,CD4＋/CD8＋） distribution on patients with chronic obstructive pulmonary disease.Methods：38 patients with chronic obstructive pulmonary disease were mensurated T lymphocyte subsets;according to the patients height,weight and albumin,the patients were divided into two groups,normal nutrition and malnutrition,analyzed the relationship between nutritional status and T lymphocytes subsets.Results：Malnourished group CD3＋,CD4＋,CD4＋/CD8＋ ratio was significantly lower than the normal nutrition group（P0.01）,while CD8＋ no significant change（P0.05）.Conclusion：In patients with chronic obstructive pulmonary disease,the malnutrition affects the distribution of T lymphocyte subsets,resulting in decreased immune function.
出处
《中国当代医药》
2010年第36期46-47,共2页
China Modern Medicine
关键词
慢性阻塞性肺疾病
营养状况
T淋巴细胞亚群
Chronic obstructive pulmonary disease
Nutritional status
T lymphocyte subsets
