摘要
β－环糊精键合硅胶经对甲苯磺酰化后， 与８－羟基喹啉反应得到８－羟基喹啉衍生化β－环糊精键合硅胶固定相（ＱＣＤＳ）． 采用元素分析、热分析及固体核磁波谱对键合固定相进行表征． 考察了ＱＣＤＳ对位置异构体、丹磺酰化氨基酸异构体、苯丙酸类药物和核苷等的分离性能．
Quinolinol derivatized β cyclodextrin bonded silica(QCDS) has been prepared for high performance liquid chromatography. The resulting bonded silica was characterized by using elemental analysis, thermal analysis and solid state NMR. The separation performance of QCDS for positional isomers, dansylamino acids, phenylpropionic acids and nucleosides was investigated. It was found that the retention of p nitroaniline and p nitrophenol was much smaller on the QCDS than on β cyclodextrin bonded silica(CDS), whereas the retention of their ortho and meta isomers was similar on the both bonded stationary phases.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
1999年第11期1708-1713,共6页
Chemical Journal of Chinese Universities
基金
国家自然科学基金
留学回国人员资助基金
中国科学院武汉物理研究所国家重点实验室基金
