摘要
基于头孢他啶将Fe3+还原为Fe2+,生成的Fe2+与2,2′-联吡啶形成桔红色配合物,建立了Fe2+-2,2′-联吡啶分光光度法测定头孢他啶的新方法,头孢他啶标准溶液质量浓度在0.4～10 mg/L范围内与吸光度呈良好线性关系,线性回归方程为ΔA=0.079 73ρ+0.045 08,线性相关系数r=0.996 0。该法用于针剂中头孢他啶的含量分析,结果令人满意。
A new method for the determination of ceftazidime by spectrophotometry was developed based on Fe^3＋ as the oxidizer of ceftazidime and 2,2′-dipyridine as the coloring reagent of Fe^2＋ , which was produced from Fe^3＋. Under the optimum conditions, the relationship between the ahsorbance and the concentration of ceftazidime was linear in the range of 0.4-10 mg/L, the regression equation was △A= 0. 079 73ρ（mg/L） ＋0. 045 08, and the relative coefficient was 0. 996 0. The proposed method has been applied to the determination of ceftazidime content in samples with satisfactory results.
出处
《淮海工学院学报（自然科学版）》
CAS
2010年第4期37-39,共3页
Journal of Huaihai Institute of Technology:Natural Sciences Edition
基金
江苏省高校自然科学研究计划资助项目(09KJD430002)
淮海工学院自然科学基金资助项目(Z2007045)
