摘要
We designed and synthesized 5 new compounds. Their chemical structures were confirmed by means of MS, HNMR andelemental analysis. FPA was tested for positive inotropic activity. The results showed that FPA could increase the contrastive amplitudeof isolated atrium of guinea pigs and had no influence upon rhythm of the hearts.
We designed and synthesized 5 new compounds. Their chemical structures were confirmed by means of MS, HNMR andelemental analysis. FPA was tested for positive inotropic activity. The results showed that FPA could increase the contrastive amplitudeof isolated atrium of guinea pigs and had no influence upon rhythm of the hearts.
出处
《化学研究与应用》
CAS
CSCD
1999年第5期523-524,共2页
Chemical Research and Application
关键词
取代芳甲酰基
哌嗪衍生物
正性肌力药
维司力农
substitoted aroyl piperazine derivatives, positive inotropic activity, synthesis
