摘要
目的 探讨白癜风进展相关的可能危险因素.方法 采用问卷调查方式获得1088例白癜风患者的临床资料,对同病程白癜风患者进展的可能诱因与皮损面积的相关性进行统计分析,有无诱因的二组间患者的比较采用平均受累面积指数的配对t检验.结果 有家族史与无家族史患者组间平均受累面积指数差异无统计学意义（t=1.499,P＞0.05）;有同形反应与无同形反应患者组的平均受累面积指数差异有统计学意义（t=6.770,P＜0.01）,且有同形反应患者组平均受累面积指数更高;伴精神因素与无精神因素影响的患者组间平均受累面积指数差异有统计学意义（t=6.704,P＜0.01）.结论 有精神因素影响或同形反应的患者白斑进展较快.
Objective To analyse the possible risk factors associated with the progression of vitiligo.Methods A questionnaire survey was carried out to collect the clinical data on 1088 patients with vitiligo.The relationship between possible inducements to the progression of vitiligo and lesion area was statistically analyzed in patients with the same clinical course of vitiligo. Paired t test was performed to compare the mean area index of involvement between patients with inducements and those without Results A significant difference was observed in the mean area index of involvement between patients with isomorphic response and those without （t = 6.770, P ＜ 0.01 ） as well as between patients negatively affected by psychiatric factors and those unaffected （t = 6.704, P ＜ 0.01 ）, but not between patients with family history and those without （t = 1.499,P ＞ 0.05）. Conclusion A rapid progression of vitiligo is more likely to be observed in patients negatively affected by psychiatric factors and patients with isomorphic response.
出处
《中华皮肤科杂志》
CAS
CSCD
北大核心
2011年第1期52-54,共3页
Chinese Journal of Dermatology
