摘要
目的比较舒芬太尼和瑞芬太尼对全身麻醉患者苏醒期的影响。方法将100例择期行骨科手术的患者随机分为舒芬太尼(SF)组和瑞芬太尼(RF)组,每组50例。SF组输注舒芬太尼0.5μg/(kg.h),RF组输注瑞芬太尼0.3μg/(kg.min)。观察记录手术结束后的呼吸恢复时间、呼之睁眼时间、拔出气管导管时间以及术后的疼痛语言(VRS)分级评分和镇静(SS)评分。观察苏醒期内躁动、恶心、呕吐、噩梦、瘙痒以及拔管后嗜睡等不良反应。结果两组患者术后呼吸恢复时间、睁眼时间、拔出气管导管时间均无显著差别,RF组术后躁动发生率、疼痛发生率显著高于SF组(P<0.01),SF组镇静强度显著强于RF组(P<0.01)。结论舒芬太尼全身麻醉与瑞芬太尼全身麻醉相比,使用前者的患者苏醒期更平稳。
Objective To compare the effects of sufentanil with remifentanil on recovery of patients after general anesthesia.Methods 100 patients scheduled for orthopedics surgery were randomized to two groups：sufentanil（SF）group and remifentanil（RF）group.In the SF group,sufentanil 0.5 μg/（kg.h） were infused.In the RF group,remifentanil 0.3 μg/（kg.min） were infused.After surgery,verbal rating scale（VRS） score,sedation score（SS）,the time of regain spontaneous breathing,opening eyes and extubation were recorded.Results There were no significant differences in the time of regain spontaneous breathing,opening eyes and extubation.VRS scores were significantly greater and SS were notablely lower during the first 6 h after extubation in the RF group than in the SF group（P〈0.01）.Incidence of restlessness after surgery were strikingly higher in the RF group than in the SF group（P〈0.01）.Conclusion Sufentanil general anesthesia is more effective for recovery of patients than remifentanil general anesthesia.
出处
《重庆医学》
CAS
CSCD
北大核心
2010年第24期3312-3313,3316,共3页
Chongqing medicine
关键词
舒芬太尼
瑞芬太尼
苏醒
sufentanil
remifentanil
analepsia
