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共焦显微镜在真菌性角膜炎临床诊断中的应用 被引量:62

Clinical diagnosis of fungal keratitis by confocal microscopy
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摘要 目的评价共焦显微镜(confocalmicroscopy)在真菌性角膜炎(fungalkeratitis)临床诊断中的应用价值。方法利用共焦显微镜对临床拟诊为真菌性角膜炎的43例患者进行检查,并用双盲法同时行涂片或活体检查真菌菌丝,对两组结果进行比较。结果43例患者中,31例行共焦显微镜检查可见真菌,综合各项检查结果并结合临床表现,32例确诊为真菌性角膜炎,共焦显微镜的确诊率为969%。结论共焦显微镜检查是一种快速、有效和无损害的活体检查手段,在真菌性角膜炎的早期诊断、治疗和研究中将起重要作用。 Objective To illustrate the value of confocal microscope in the diagnosis of fungal keratitis. Methods In vivo confocal microscopy was performed on 43 patients of suspected fungal keratitis. The results were compared to that of smears and biopsies. Results Fungal filaments were imaged in 31 of 43 patients′ corneas. Fungal keratitis was diagnosed in 32 patients based on clinical signs and all the methods of examinations. The positive rate of confocal microscopy is 96.9%. Conclusion Confocal microscopy can be a rapid, effective and noninvasive imaging technique, and it is helpful in the diagnosis, treatment and study of fungal keratitis.
出处 《中华眼科杂志》 CAS CSCD 北大核心 1999年第1期7-9,I003,共4页 Chinese Journal of Ophthalmology
关键词 真菌性角膜炎 角膜炎 诊断 共焦显微镜 Microscopy, confocal Cornea Eye infections, fungal
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