摘要
近年来，随着人们对肿瘤发病机制的进一步认识，以及对肿瘤细胞信号通路研究的深入，开始了以细胞受体、关键基因和调控分子为靶点的治疗，并称之为“靶向治疗”，然而靶点分子的基因多态性决定了靶向药物治疗的有效性。文章概述肿瘤靶向治疗中基因多态性检测的意义。
In recent years, the study on the molecular mechanism of tumorigenesis and cancer cell signals promotes the application of cancer-targeted therapy, which aims at cell receptors, key genes, and regulatory molecules in cancer cells. However, the polymorphism of targeting genes/molecules determines the clinical efficiency of these therapies. The application of gene polymorphism diagnosis in cancer-targeted therapy was reviewed.
出处
《肿瘤研究与临床》
CAS
2010年第11期721-723,共3页
Cancer Research and Clinic
关键词
分子检测
肿瘤
个体化
靶向治疗
Molecular diagnosis
Neoplasms
Personalized
Target therapy
