摘要
目的:观察异维A酸红霉素凝胶治疗轻、中度寻常痤疮的疗效。方法:将50例轻、中度面部寻常痤疮患者按面部左右侧分为2组,治疗组:左侧面部外用异维A酸红霉素凝胶,每晚1次;对照组:右侧面部外用维胺脂维E乳膏,每晚1次。比较第6周和第8周2组疗效。结果:治疗第6周时,治疗组与对照组的有效率分别为70%、42%(P<0.05);治疗第8周时,治疗组与对照组的有效率分别为82%、76%(P>0.05);对于炎性皮损,在治疗第6、8周时,2组疗效差异有统计学意义(P<0.05)。结论:异维A酸红霉素凝胶治疗轻、中度痤疮疗效确切,起效较维胺脂维E乳膏快。当皮损以炎性丘疹为主时,异维A酸红霉素凝胶疗效优于维胺脂维E乳膏。
OBJECTIVE： To observe therapeutic effect of Isotretinoin erythromycin gel in the treatment of medium and mild vulgaris acne. METHODS： 50 patients with vulgaris acne were divided into 2 groups： treatment group were treated with Isotretinoin erythromycin gel on the left face one time per night, and control group were externally treated with Viaminate vitamin E cream on the right face one time per night. The therapeutic efficacy was observed and compared after 6 weeks and 8 weeks respectively. RESULTS： The total effective rate of treatment group was 70% and that of control group was 42% in 6th week（P〈0.05）. After 8 weeks of treatment, the total effective rate of treatment group was 82% and that of control group was 76% （P〉0.05）. After 6 weeks and 8 weeks of treatment, there were significant differences in therapeutic efficacy on inflammatory acne between treatment group and control group （P〈0.05）. CONCLUSION： Isotretinoin erythromycin gel is effective and faster than Viaminate vitamin E cream in the treatment of medium and mild vulgaris acne. Isotretinoin erythromycin gel shows superior efficacy compared with Viaminate vitamin E cream for inflammatory ache.
出处
《中国药房》
CAS
CSCD
北大核心
2011年第2期155-157,共3页
China Pharmacy
