摘要
目的:探讨大肠鳞状细胞癌的临床表现、病理形态特征、治疗及预后。方法:对1例直肠鳞状细胞癌病例进行组织形态学、免疫组织化学分析结合原位杂交HPV16/18检查,并复习相关文献。结果:大肠鳞状细胞癌常见于40-50岁年龄组患者,男性略多,多见于乙状结肠和直肠,形态学表现为不同分化程度的鳞状细胞癌,表达鳞状细胞癌标记如p63,CK5/6;个别病例可见HPV16感染。结论:大肠鳞状细胞癌是一种罕见病变,临床表现与常见的腺癌相似,外科手术为最有效的治疗,预后较腺癌差;有时内窥镜镜下易与间质瘤误诊。
Objective ： To investigate the clinic - pathological features, diagnosis and prognosis of intestinum erassum suqamous cell carcinoma（see）. Methods：A case of intestinum crassum suqamous cell carcinoma was reported, based on histological and immunohistochemical studies and the literature was reviewed. Results：Primary intestinum crassum suqamous cell carcinoma occur most commonly in the fifth decade of life with a slight predominance for men. The tumors histologic appearances was well or poorly differentiation,tumor cell showed positive for p63 and CK5/6; HPV16 was detected in a few of cases. Condusion：lntestinum crassum see is a rare tumor with an aggressive course; clinical features are similar with adenocarcinoma, the prognosis is worse; surgery is the most effective therapy, and adjuvant chemotherapy and radiotherapy shoould be considered; sometimes.
出处
《现代肿瘤医学》
CAS
2011年第1期94-96,共3页
Journal of Modern Oncology
关键词
大肠
直肠
乙状结肠
鳞状细胞癌
intestinum crassum
rectum colon
sigmoid colon
see
