摘要
目的:观察活血解毒方对实验性糖尿病大鼠的降血糖作用。方法:对大鼠一次性腹腔注射链脲佐菌素(Streptozocin,STZ)30mg.kg-1建立糖尿病(diabetes mellitus,DM)模型,将建模成功的大鼠随机分为6组,另设正常对照组,连续给药30d,在相应时间点测随机血糖、体重、做糖耐量试验。结果:灌服活血解毒方各剂量组的血糖明显低于模型组;活血解毒方减缓糖尿病大鼠体重下降,对糖耐量具有显著的改善作用。结论:活血解毒方的降血糖作用比较显著。
Objective：To observe the effect of Huoxuejiedu Decoction on reducing blood sugar function of rats suffering from diabetes mellitus by experiences.Methods：Rats were injected 30mg/kg without a second time by using strepozocin（STZ） to establish rat model of diabetes mellitus and were randomly divided into six groups,additionally establishing the control group,continully infusing rats with drugs 30days,gauging random blood sugar,measuring weight and doing glucose tolerance test.Results：The blood sugar density of rat＇s which were infused with respective dose of HXJD Decoction group was significantly lower than that of diabetes mellitus of model group（P﹤0.05）.HXJD Decoction group can not only slow down the drop of diabetic rats＇weight,but also obviously improve their glucose tolerance＇s capacities.
出处
《中医药学报》
CAS
2010年第6期20-22,共3页
Acta Chinese Medicine and Pharmacology
基金
国际科技合作项目:基于互信息理论的中药复方效应成分及其机制研究项目(编号:20071664)
关键词
活血解毒方
链脲佐菌素
降血糖
Huoxuejiedu Decoction
Streptozocin
Reduce blood sugar
