摘要
通过十八烷基聚氧乙烯和环氧氯丙烷的封端反应制备了α－环氧基－ω－十八烷基聚氧乙烯大单体．并采用ＢＦ３·Ｅｔ２Ｏ引发ＴＨＦ和大单体共聚合，得到了梳状的十八烷基聚氧乙烯接枝共聚醚．以该共聚醚为软段合成了十八烷基和聚氧乙烯复合修饰的聚氨酯（ＰＥＵ－ｇ－ＰＥＯ－Ｃ１８）．通过血小板粘附试验对材料的体外抗凝血性实验结果表明，采用具有选择性吸附白蛋白功能的十八烷基和ＰＥＯ复合修饰聚氨酯，材料表面血小板粘附量明显减少．
A new grafted polyether, poly(tetramethylene glycol) graft ω stearyl poly(ethylene glycol)(PTMG g PEG C 18 ), was synthesized by the cationic polymerization of α ω bifunctional PEG macromonomer and THF. Polyurethane graft ω stearyl poly(ethylene glycol)(PEU g PEO C 18 ), the new polyether as a soft segment, was synthesized. The results of platelet adhesion on PEU g PEG C 18 surface indicated that the polyurethane can resist platelet adhesion on the original surface and pre adsorption albu min surface.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
1999年第5期814-818,共5页
Chemical Journal of Chinese Universities
基金
国家自然科学基金
