摘要
1例47a女性患者,因右乳癌术后3年,发现全身多发骨转移3月余入院。入院后,给予多西他赛联合顺铂方案化疗,常规水化和利尿止吐,化疗期间加用伊班膦酸钠抗骨转移治疗。临床药师把化疗过程中可能出现的不良反应的预防与处理及药物选择作为药学监护点,建议医生常规使用泮托拉唑保护胃黏膜,避免奥美拉唑对多西他赛代谢的影响。建议选用肾毒性较小的伊班膦酸钠,以减轻患者肾损害,患者最终顺利完成本周期治疗。
A 47-year-old female patient who had suffered from breast cancer operation 3 years ago,with multiple bone metastasis for 3 months was hospitalized for further treatment.After admission,she received docetaxel and DDP chemotherapy,with routine hydration,diuresis,anti-vomiting drugs and ibandronate monosodium injection to resist osseous metastasis.The clinical pharmacist implemented pharmaceutical care points in respect of the prevention and treatment of adverse drug reactions and drug selection,and suggested adjusting omeprazole to pantoprazole to avoid the influence of omeprazole on the metabolism of docetaxel,and using ibandronate monosodium injection to resist osseous metastasis.At last,the cycle of chemotherapy for the patient was successfully finished.
出处
《中国药物应用与监测》
CAS
2010年第3期175-176,共2页
Chinese Journal of Drug Application and Monitoring
关键词
临床药师
乳腺癌
多西他赛
药学监护
Clinical pharmacist
Breast cancer
Docetaxel
Pharmaceutical care
