摘要
目的:探讨高血压脑内出血患者血管破裂的发生机理。方法:正常脑血管,高血压脑出血患者出血部位的脑动脉分别进行TUNEL染色,计数血管平滑肌细胞凋亡比例。结果:高血压脑出血患者血管平滑肌细胞凋亡百分比为70.00±2.60,正常脑血管平滑肌细胞凋亡百分比为14.29±2.60。结论:血管平滑肌细胞凋亡与高血压脑内出血患者相关。
Objective:To study the mechanism of blood vessel rupture in patients with hypertensive in tracerebral hemorrhage.Methods:TUNEL staining and counting of apoptosis percentage in vascular smooth muscle cells were carried out in normal and hypertensive intracerebral hemorrhage growps.Results: In hypertensive cerebral hemorrhage,vascular smooth muscle cell apoptosis was 70.00 ± 2.60%;in normal brain,vascular smooth muscle cell apoptosis was 14.29 ± 2.60%.Conclusion: Apoptosis of vascular smooth muscle cells was associated with hypertensive intracerebral hemorrhage.
出处
《泸州医学院学报》
2010年第6期614-616,共3页
Journal of Luzhou Medical College
基金
四川省卫生厅资助项目(No:80174)
关键词
凋亡
脑内出血
血管平滑肌细胞
Apoptosis; Intracerebral hemorrhage; Vascular smooth muscle cells;