摘要
目的评价布托啡诺用于预防和治疗上消化道手术全麻患者术后躁动的有效性与安全性。方法ASAⅠ、Ⅱ级上消化道择期手术患者50例,随机分为对照(C)组与布托啡诺(B)组,每组25例。在术毕停用麻醉药即刻,C组经静脉注射生理盐水2mL;B组静脉注射布托啡诺0.02mg/kg。记录停用麻醉药前、拔管即刻、拔管后5min时的心率(HR)、血压(SBP),并对循环稳定程度、躁动程度、镇静状态进行评分。结果两组患者HR、SBP在停药前差异无显著性(P>0.05),B组在拔管即刻HR、SBP较停药前明显升高(P>0.05)。与麻醉前相比,拔管后5minB组HR、SBP相对平稳,两组比较差异无显著性(P>0.05)。与C组比较,B组躁动发生率降低,而镇静评分升高,两者均差异有显著性(P<0.05)。结论布托啡诺可以降低上消化道术后躁动的发生率,值得临床推广应用。
【Objective】To evaluate the effect of butorphanol on prevention and treatment of agitation in upper gastrointestinal patients. 【Methods】50 ASA Ⅰ ～ Ⅱ grade of upper digestive tract patients undergoing elective surgery were randomly divided into control （C） group and butorphanol （B） groups, each with 25 cases. After stopping the anesthetics when surgery was over, group C intravenously were injected of normal saline 2 mL,while group B were injected with butorphanol 0.02 mg/kg. We recorded HR and SBP before and after extubation, and circulation stability, agitation score and sedation score. 【Results】The two groups with no difference in HR and SBP before the withdrawal extubation （P 0.05）. In group B,HR, SBP at the time of extubation were significantly higher than that at the time of stopping anesthetics （P 0.05）. But compared with the extubation, the HR and SBP in extubation after 5 min in relatively stable, the two groups showed no significant difference （P 0.05）. Compared with the group C, group B showed a lower incidence of agitation and a higer sedation score higher, both statistically significant （P 0.05）. 【Conclusions】Butorphanol can reduce the incidence of agitation rate in upper gastrointestinal and worthy to be popularized.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2010年第5期775-777,共3页
China Journal of Modern Medicine
关键词
布托啡诺
上消化道手术
苏醒期
躁动
butorphanol
upper gastrointestinal surgery
recovery period
agitation
