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氟代脱氧葡萄糖在PET/CT致痫灶定位显像中的应用 被引量:1

Application of 18S F-FDG PET/CT in epileptogenic zone localization
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摘要 目的探讨正电子药物18F氟代脱氧葡萄糖(18F-FDG)在正电子发射计算机(断层PET/CT)脑显像致痫灶定位中的应用。方法对32例癫痫患者行18F-FDG脑三维PET/CT显像,将其定位结果与头皮脑电图(EEG)、颅脑CT或MRI结果进行比较。结果PET/CT阳性检出率为90.6%(29/32),其中低代谢灶27例,高代谢灶2例,正常3例;EEG阳性检出率为65.6%(21/32),常规脑部CT或MRI阳性检出率为31.0%(10/32)。结论18F-FDG在PETJCT脑显像中对癫痫的定位诊断有较高的灵敏性和准确性。 Objective To discuss the application of 18 F-FDG PET/CT in epileptogenie zone localization. Methods Tirty-two patients with epilepsies were studied with interietal 18F-FDG PET/CT cerebral imaging, and all of them had scalp EEG, CT or MRI results for eomparision. Results The sensitivity of 18F-FDG PET/CT was 90. 6% ,27 patients(84.5% ) showed focal hypometabolism,2 patients(6. 3% ) showed focal hypermetabohsm and rest 3 patients (9. 4% ) had negative result. The sensitivity of EEG was 65.6% (21/32), the sensitivity of CT and MRI was 31.0% (10/32). Conclusion 18F-FDG PET/CT was a sensitive and accurate image modality in the localization of epileptle loci.
出处 《中国基层医药》 CAS 2010年第21期2919-2920,3026,共3页 Chinese Journal of Primary Medicine and Pharmacy
关键词 氟脱氧葡萄糖F18 正电子发射断层显像技术 Fluorodeoxyglueose F18 Positron-emission tomography
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