期刊文献+

子宫内膜异位症患者血清癌抗原125检测的临床意义

Clinical significance of serum CA125 in patients with endometriosis
原文传递
导出
摘要 目的探讨子宫内膜异位症患者血清癌胚抗原125(CAl25)水平变化及临床意义。方法回顾性分析76例子宫内膜异位症患者血清CAl25水平,并对其中28例子宫内膜异位症复发患者及80例健康体检者血清CAl25水平进行分析。结果76例子宫内膜异位症患者中有42例的血清CAl25值高于正常值(35kU/L),敏感性为55.2%,Ⅲ-Ⅳ期子宫内膜异位症组敏感性(64.8%)较Ⅰ~Ⅱ期组敏感性(45.6%)明显增高(P〈0.01);28例复发性子宫内膜异位症患者中有20例患者血清CAl25值≥35kU/L,敏感性为71.4%,CAl25值预测Ⅲ-Ⅳ期组复发的敏感性(93.7%)明显高于Ⅰ-Ⅱ期组敏感性(41.6%)(P〈0.01)。结论子宫内膜异位症患者血清CAl25检测对子宫内膜异位症复发的预测亦有一定的价值。 Objective To investigate the clinical significance and level variation of serum CA125 in patients with endometriosis. Methods Serum CA125 level of 28 recurrent cases,76 endometriosis cases and 80 healthy cases were retrospectively analyzed. Results In 76 endometriosis cases,the level of serum CA125 of 42 cases was over 35 kU/L,the sensitivity was 55.2% ,the sensitivity of stageⅢ-Ⅳ(64. 8% ) was obviously higher than that of stage Ⅰ-Ⅱ (45.6%) ;In 28 recurrent cases,the values of serum level CA125 of 20 cases were over 35 kU/L,the sensitivity was 71.4% ,and the prediction ability of CA125 in stage Ⅲ-Ⅳ(93.7% ) was obviously higher than that in stage Ⅰ-Ⅱ (41. 6% ). Conclusion Serum CA125 played an important role in the diagnosis and prediction of endometriosis.
作者 潘恩云
出处 《中国基层医药》 CAS 2010年第21期2883-2884,共2页 Chinese Journal of Primary Medicine and Pharmacy
关键词 子宫内膜异位症 癌胚抗原 Endometriosis Carcinoembryonic antigen
  • 相关文献

参考文献17

  • 1Moss EL,Hollingworth J,Reynolds TM.The role of CA125 in clinical practice.J Clin Patho1,2005,58(3):308-312.
  • 2Barbieri RL,Niloff JM,Jr Bast R,et al.Elevated serum concentrations of CA-125 in patients with advanced endometriosis.Fertil Steril,1986,45(5):630-634.
  • 3Muyldermans M,Cornillie FJ,Koninckx PR.CA125 and endometriosis.Hum Reprod Update,1995,1(2):173-187.
  • 4Vlahos NF,Kalampokas T,Fotiou S.Endometriosis and ovarian cancer:a review.Gynecol Endocrinol,2010,26(3):213-219.
  • 5Aris a.Endometriosis-associated ovarian cancer:A ten-year cohort study of women living in the estrie region of quebec,Canada.J Ovarian Res,2010:2.
  • 6张爱群,孙富国,王昭英.子宫内膜异位症的恶变[J].现代妇产科进展,2008,17(5):385-388. 被引量:8
  • 7Gupta D,Lis CG.Role of CA125 in predicting ovarian cancer survival-a review of the epidemiological literature.J Ovarian Res,2009,2(1):13.
  • 8姚春凤.血清癌抗原125对卵巢恶性肿瘤诊断及监测复发的价值[J].江苏预防医学,2004,15(2):9-10. 被引量:1
  • 9聂宇波,谢海燕,曾频频,钟磊,刘卫兰,李文华,邱玉梅.子宫肌腺症和子宫内膜异位症患者血清CA125检测的临床意义[J].检验医学,2008,23(6):674-676. 被引量:15
  • 10Somigliana E,Vigano P,Tirelli AS,et al.Use of the concomitant serum dosage of CA 125,CA 19-9 and interleukin-6 to detect the presence of endometriosis.Hum Reprod,2004,19(8):1871-1876.

二级参考文献119

共引文献95

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部