摘要
目的探讨子宫内膜异位症患者血清癌胚抗原125(CAl25)水平变化及临床意义。方法回顾性分析76例子宫内膜异位症患者血清CAl25水平,并对其中28例子宫内膜异位症复发患者及80例健康体检者血清CAl25水平进行分析。结果76例子宫内膜异位症患者中有42例的血清CAl25值高于正常值(35kU/L),敏感性为55.2%,Ⅲ-Ⅳ期子宫内膜异位症组敏感性(64.8%)较Ⅰ~Ⅱ期组敏感性(45.6%)明显增高(P〈0.01);28例复发性子宫内膜异位症患者中有20例患者血清CAl25值≥35kU/L,敏感性为71.4%,CAl25值预测Ⅲ-Ⅳ期组复发的敏感性(93.7%)明显高于Ⅰ-Ⅱ期组敏感性(41.6%)(P〈0.01)。结论子宫内膜异位症患者血清CAl25检测对子宫内膜异位症复发的预测亦有一定的价值。
Objective To investigate the clinical significance and level variation of serum CA125 in patients with endometriosis. Methods Serum CA125 level of 28 recurrent cases,76 endometriosis cases and 80 healthy cases were retrospectively analyzed. Results In 76 endometriosis cases,the level of serum CA125 of 42 cases was over 35 kU/L,the sensitivity was 55.2% ,the sensitivity of stageⅢ-Ⅳ(64. 8% ) was obviously higher than that of stage Ⅰ-Ⅱ (45.6%) ;In 28 recurrent cases,the values of serum level CA125 of 20 cases were over 35 kU/L,the sensitivity was 71.4% ,and the prediction ability of CA125 in stage Ⅲ-Ⅳ(93.7% ) was obviously higher than that in stage Ⅰ-Ⅱ (41. 6% ). Conclusion Serum CA125 played an important role in the diagnosis and prediction of endometriosis.
出处
《中国基层医药》
CAS
2010年第21期2883-2884,共2页
Chinese Journal of Primary Medicine and Pharmacy
关键词
子宫内膜异位症
癌胚抗原
Endometriosis
Carcinoembryonic antigen