摘要
目的:探讨双b值对比法在肝脏局灶性病变诊断中的价值。方法:回顾性分析108例行肝脏MRI平扫及动态增强扫描患者的病例(肝癌44例,转移瘤4例,血管瘤40例,囊肿18例,局灶性结节增生2例),分为良恶性两组(恶性组48例,A组;良性组60例,B组),均行b值为500和800 s/mm2的DWI扫描,测量肝脏病变的信号强度值,计算相对信号比R500、R800(R=病灶信号/背景信号),观察不同b值时病变的信号变化情况ΔR(ΔR=R800-R500)。采用χ2检验分析采用ΔR值诊断良恶性病变与病理结果的一致性。结果:ΔR≥0.25有42例(PA组),ΔR<0.25(PB组)有66例,其中PA中有4个为良性病变(均为血管瘤),PB中有10个为恶性病变(2个转移瘤,8个肝癌),差异无统计学意义(χ2=1.786,P>0.05)。结论:双b值对比法在肝脏局灶性病变的定性诊断中具有可行性。
Objective：To investigate the double b value of diffuse weighted imaging （DWI） in the diagnosis of hepatic nodular lesions. Methods： 108 patients including liver carcinoma （n =44） ,hepatic metastasis （n=4） ;cavernous hemangioma （n=40） ,liver cyst （n=18） and focal nodular hyperplasia （FNH,n 2） underwent plain and dynamic Gd DTPA enhanced MR scanning of the liver for hepatic nodular lesion detection were retrospectively analyzed. The patients were divided into two groups with malignant lesion （group A, 48 cases） and benign lesion （group B, 60 cases）. The signal intensities of hepatic lesions were measured, and the relative signal ratio （△R） as R500 and R800 （R= lesion signal/background signal） were cal culated. The change of signal （△R） with different b value （△R=R800 R500） were observed. Using Chi square test to analyze the value of △R in the diagnosis of malignant/benign lesion and correlated with pathology. Result： There were △R≥ 0.25 （n=42）,△RG0.25 （n= 66） ,42 cases were showed as malignant with4 false positives,and 66 cases were showed as benign with 10 false-negatives. No significant statistic difference was existed （ x^2 = 1.786, P 〉 0.05 ）. Conclusion ： Double b value could be used in the diagnosis of hepatic nodular lesion.
出处
《放射学实践》
北大核心
2010年第11期1253-1255,共3页
Radiologic Practice
关键词
肝肿瘤
磁共振成像
扩散加权成像
Liver neoplasms
Magnetic resonance imaging
Diffusion weighted imaging
