摘要
目的 研究实时动态血糖监测系统（RT-CGMS）与静脉血糖、毛细血管血糖检测的相关性.方法 收集2009年8至12月在哈尔滨医科大学附属第二医院治疗的33例糖尿病患者佩戴5 dRT-CGMS,期间测定静脉和毛细血管血糖值.应用相关分析、Clarke误差表格分析、Bland-Altman分析比较RT-CGMS与静脉血糖及毛细血管血糖的相关性 计算患者佩戴RT-CGMS期间的平均血糖波动幅度（MAGE）.结果 （1）RT-CGMS与静脉、毛细血管血糖值的相关系数分别为0.936和0.933（均P〈0.01）.（2）Clarke误差表格分析显示静脉组和毛细血管组分别有98.67%和98.64%的点位于A区（临床准确区）与B区（临床可接受区） 没有点位于C区（数据误差区） 分别有1.33%和1.36%的点位于D区（数据错误区）.（3）Bland-Altman分析RT-CGMS与静脉血糖、毛细血管血糖值在（x）±1.96范围内.（4）MAGE相同的患者HbA1c差异较大.结论 RT-CCMS与静脉血糖、毛细血管血糖检测具有良好的相关性、准确性和一致性.
Objective To study the correlation of real-time continuous monitoring system （RT-CGMS） with venous glucose and capillary glucose values. Methods A total of 33 diabetics received RT-CGMS for 5 days. Fasting venous glucose values were measured at Days 1, 3 and 5 and capillary glucose values recorded 7 times daily. The methods of correlation coefficient, error grid analysis（EGA） and BlandAltman analysis were employed to assessed the correlation, accuracy and agreement of RT-CGMS with venous glucose and capillary glucose values respectively. The mean amplitude of glucose excursions （MAGE） was calculated during RT-CGMS testing periods. Results （1） The correlation coefficient of RT-CGMS with vein glucose and capillary glucose values were 0. 936, 0. 933 （P 〈 0. 01） （2） The analysis results of EGA showed that 98. 67%, 98. 64% of venous and capillary values fell in the A and B zones and 1. 33%,1.36% fell in the D zone （3） The agreement analysis showed that RT-CGMS readings were in close agreement with venous glucose and capillary glucose results （4） The patients at the same M AGE levels had obvious differences in HbAlC. Conclusion There is a high level of correlation, accuracy and agreement between RT-CGMS and venous glucose and capillary glucose values.
出处
《中华医学杂志》
CAS
CSCD
北大核心
2010年第42期2971-2975,共5页
National Medical Journal of China
基金
基金项目：美国亚洲糖尿病研究基金会科研项目（2009-08.12）
哈尔滨市科技攻关项目（2007AA3CS084）
上海市新兴前沿技术联合攻关项目（SHDCl2006101）
关键词
糖尿病
血糖自我监测
血糖波动
Diabetes mellitus Boold glucose self monitoring Boold glucose fluctuation
