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165例甲状腺硬度不同的Graves病患者^(131)I治疗效果观察 被引量:4

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摘要 目的观察131I治疗Graves病的效果及甲状腺硬度对其的影响。方法对165例甲状腺硬度不同的Graves病患者[质地为软65例(质软组)、韧70例(质韧组)、硬30例(质硬组)]行131I治疗,131I治疗剂量按个体计算法确定;治疗后6个月根据游离三碘甲腺原氨酸(FT3)、游离甲状腺素(FT4)、促甲状腺激素(TSH)水平判定甲状腺功能减退症(甲减)发生率及疗效,并采用Spearman相关分析法对甲状腺硬度与治愈率、甲减率行相关分析。结果治愈率及甲减发生率在质软组、质韧组、质硬组均逐渐降低(P<0.01、0.05),甲状腺硬度与治愈率、甲减率均呈高度负相关(r均=-1,P=0.000)。结论 131I治疗Graves病效果确切,随甲状腺硬度增加治愈率和甲减发生率均下降;临床可根据甲状腺硬度调节131I治疗剂量。
出处 《山东医药》 CAS 北大核心 2010年第43期64-65,共2页 Shandong Medical Journal
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  • 1招钜泉,张少丰.探讨TRAB检测在Grave's病中的临床意义[J].国际医药卫生导报,2005,11(2):89-91. 被引量:2
  • 2黄昭穗,黄春红.甲状腺疾病患者322例TSH受体抗体测定的临床意义[J].实用医学杂志,2005,21(9):912-912. 被引量:2
  • 3Gilmour J, Bmwnlee Y, Foster P, et al. The Quantitative Measurement of Auto - antibodies to Thyroglobulin and Thyroid Peroxidase by Automated Micro -particle Based Immunoassays in Hashimoto's Disease, Graves'Disease and a Follow- up Study on Postpartum Thyroid Disease [ J ]. Clin Lab, 2000, 46(1 -2): 57-61.
  • 4Gonzalez C, Hernando M, Cava F, et al. Biological Variability of Thyroid Auto - antibodies ( Anti - TPO and Anti - Tg) in Clinically and Biochemically Stable Patients with Autoimmune Thyroid Disease [ J]. J Clin Lab Analy, 2002, 16(1): 37-39.
  • 5Melntosh RS, Asghar MS, Weetman AP. The Antibody Response in Human Autoimmune Thyroid Disease[ J]. Clin Sci (Colch), 1997, 92:529-541.
  • 6Dai Y, Carayanniotis KA, Eliades P, et al. Enhancing or Suppressive Effects of Antibodies on Prosessing of a Pathogenic T Cell Epitope in Thyroglobulin [ J ]. J Immunol, 1999, 162: 6987- 6992.
  • 7Iagaru A,McDougall IR.Treatment of Thyrotoxicosis[].The Journal of Nuclear Medicine.2007
  • 8Nieuwlaat W,Hermus AR,Ross HAL,et al.Dosimetry of radioiodine therapy in patients with nodular goiter after pretreatment with a single,low dose of recombinant human thyroid-stimulating hormone[].The Journal of Nuclear Medicine.2004
  • 9Ripley SD,John E,Freitas,Nagle CE.Is Thyroid scintigraphy necessary before I-131therapy for hyperthyroidism concise communication[].The Journal of Nuclear Medicine.1982
  • 10B Pena,S Arum,M Cross,et al.123I Thyroid uptake and thyroid size at24,48,and72hours after the administration of recombinant human thyroid-stimulating hormone to normal volunteers[].The Journal of Clinical Endocrinology.2006

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