摘要
目的 探讨肉芽肿性小叶性乳腺炎的临床病理特点.方法 对68例经组织病理学证实的肉芽肿性小叶性乳腺炎的临床和组织病理学资料进行回顾性分析.结果 68例患者均为女性,大部分有哺乳史,以乳腺肿块就诊,伴皮肤破溃9例,均不伴特殊感染.组织病理特点为以乳腺终末导管小叶单位为中心的肉芽肿性炎,小叶结构通常存在,小叶内可见以中性粒细胞为主的炎性细胞浸润.随访6～36个月,复发4例.结论 肉芽肿性小叶性乳腺炎与乳腺癌在临床特征上有相似之处,易误诊,须对其镜下组织改变仔细鉴别.
Objective To study the clinical and pathologic features of granulomatous lobular mastitis （GLM）. Methods Sixty-eight cases of GLM were retrieved from the archival file. The clinical data and histologic features were retrospectively reviewed. Results Sixty-eight patients presented with breast mass. Ulceration in overlying breast skin was seen in 9 cases. Most of the patients had history of breast feeding. None of them had evidence of specific infections involving the breast. The clinical and radiologic features mimicked malignancy. Histologically, GLM was characterized by the presence of nonnecrotizing granulomas, usually admixed with neutrophils and associated with benign ductolobular units. The ductolobular architecture was still preserved. The duration of follow up ranged from 6 to 36 months. Four patients suffered from disease recurrence. Conclusions GLM shows clinical and radiologic features reminiscent of breast cancer. Correct diagnosis requires histologic examination of the biopsy specimens.
出处
《中华病理学杂志》
CAS
CSCD
北大核心
2010年第10期678-680,共3页
Chinese Journal of Pathology
关键词
乳腺疾病
肉芽肿
炎症
诊断
Breast diseases
Granulomas
Inflammation
Diagnosis
