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带形蜈蚣藻的化学成分研究 被引量：3

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摘要 目的研究南海大型经济海藻带形蜈蚣藻(Grateloupia turuturu)的化学成分。方法利用色谱、红外、质谱和核磁共振波谱等方法对带型蜈蚣藻的化学成分进行分离和结构鉴定并进行抗病毒活性研究。结果从中分离鉴定了6个化合物,分别为棕榈酸(I)、3-β-5-烯-胆甾醇(Ⅱ)、胆甾-4-烯-6-酮(Ⅲ)、胆甾-4-烯-3-酮(Ⅳ)、胆甾-4,6-二烯-3-醇(Ⅴ)和胆甾-4,6-二烯-3-酮(Ⅵ),化合物Ⅱ抗HSV-1病毒效果较好,其IC50达到7.81μg/ml。结论以上均为首次从该海藻中分离得到。化合物Ⅱ具有较好的抗病毒活性。
作者 芮雯 伍秋明 岑颖洲
机构地区 广东药学院 暨南大学
出处 《时珍国医国药》 CAS CSCD 北大核心 2010年第11期2854-2855,共2页 Lishizhen Medicine and Materia Medica Research
基金 广东省"十五"重大科技专项(2002A3050503)
关键词 带型蜈蚣藻 化学成分 抗病毒活性 HSV-1
分类号 R284.1 [医药卫生—中药学]
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参考文献17

  • 1李青选.海洋天然产物：抗艾滋病活性物质的来源[J].中国海洋药物,1993,12(3):22-26. 被引量：8
  • 2Masami shibashi,Miho Takahashi,Junichi Kobayashi.Studies on macrolides from marine dinflagellate amphidinium SP:Structures of amphidinolides R and S and a succinate feeding experiement[J].Tetrahedron,1997,53(23):7827.
  • 3Simon-Colin,Christelle; Kervarec,Nelly; Pichon,Roger; Deslandes,Eric.Purification and characterization of 4-methanesulfinyl-2-methylamino butyric acid from the red alga Grateloupia doryphora howe[J].Phytochemistry Reviews,2005,3(3):367.
  • 4Simon-Colin,Christelle; Kervarec,Nelly; Pichon,Roger; Bessieres,Marie-Anne; Deslandes,Eric.Characterization of N-methyl-L-methionine sulfoxide and isethionic acid from the red alga Grateloupia doryphora[J].Phycological Research,2002,50(2):125.
  • 5Nozaki,Hiroshi; Ohira,Susumu; Shirane,Fukue.Two new methyl sulfones from the red alga Grateloupia filicina J.Agardh[J].Fisheries Science,1998,64(3):494.
  • 6Miyazawa Keisuke,Ito,Keiji.Fac.Fish.Anim.Husb.Isolation of a new peptide,L-citrullinyl-L-arginine,from a red alga Grateloupia turuturu[J].Nippon Suisan Gakkaishi,1974,40(8):815.
  • 7Miyazawa Keisuke,Ito,Keiji.Isolation of L-methionine-l-sulfoxide and N-methylmethionine sulfoxide from a red alga Grateloupia turuturu[J].Nippon Suisan Gakkaishi,1974,40(7):655.
  • 8Hellio Claire,Simon-Colin Christelle,Clare Anthony,et al.Isethionic acid and floridoside isolated from the red alga,Grateloupia turuturu,inhibit settlement of Balanus amphitrite cyprid larvae[J].Biofouling,2004,20(3):139.
  • 9Athukorala Yasantha,Lee Ki-Whan,Shahidi Fereidoon,Heu Min Soo,Kim Hung-Tae,Lee Jung-Suck,Jeon You-Jin.Antioxidant efficacy of extracts of an edible red alga (Grateloupia filicina) in linoleic acid and fish oil[J].Journal of Food Lipids,2003,10(4):313.
  • 10郑怡,陈寅山,卢海声.SCREENING FOR ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES IN SOME MARINE ALGAE FROM THE FUJIAN COAST OF CHINA WITH THREE DIFFERENT SOLVENTS[J].Chinese Journal of Oceanology and Limnology,2001,19(4):327-331. 被引量：37

二级参考文献38

  • 1江黎明.脂肪酸抗肿瘤作用研究进展[J].湛江医学院学报,1993,11(1):46-50. 被引量：16
  • 2邓松之 苏纪兰 秦蕴珊.海洋天然产物的研究与开发[A].苏纪兰、秦蕴珊.当代海洋科学学科前沿[M].北京:学苑出版社,2000.326.
  • 3Fusetani N,Yasumuro K, et al. Kalihinene and isokalihinol B, cytotoxic diterpene isonitriles from the marine sponge Acanthella Klethra . Tetrahedron Letters, 1990,31 (25) :3599-- 3602.
  • 4Thompson JE, Walker RP, et al. A chemical defense mechanism for the nudibrance cadlina luteomarginata. Tetrahedron, 1982,38(13) : 1865-- 1873.
  • 5Hirota H,Tomono Y,et al. Terpenoid with antifouling activity against barnacle larvae from the marine sponge Acanthella cavernosa. Tetrahedron, 1996, 52 ( 7 ) : 2359-2368.
  • 6Burgoyne DL, Dumdei EJ. Acanthenes A to C: a chloro,isothiocyanate, formamide sesquiterpene isolated from the northeastern pacific marine sponge Acanthella sp. and theb Dorid Nudibranch Cadlina Luteomarginata. Tetrahedron,1993,49(21):4503-4510.
  • 7Capon RJ ,Macleod JK. New isothiocyanate sesquiterpenes from the australian marine sponge Acanthella pulcherrima. Aust J Chem, 1988,41:979--83.
  • 8Blasio BD,Fattorusso E, et al. Axisonitrile-3, axisothiocyanate-3 and axamide-3, sesquiterpenes with a novel spiro[4,5 ]-decane skeleton from the sponge Axinella cannabina. Tetrahedron , 1976,32:473--478.
  • 9Alvi KA, Tenenbaum L. Anthelmintic polyfunctional nitrogen-containing terpenoids from marine sponges. Journal of Natural Products, 1991,54 ( 1 ) : 71 - 78.
  • 10Chang CWJ, Patra A, et al. Kalihinols, multifunctional diterpenoid antibiotics from marine sponges Acanthella sp.J Am Chem Sac, 1987,109:6119-6123.

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时珍国医国药
2010年 第11期

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