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多西他赛联合吡柔比星或顺铂方案治疗晚期乳腺癌51例临床观察 被引量:3

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摘要 目的观察多西他赛联合吡柔比星或顺铂方案治疗晚期乳腺癌的临床疗效。方法晚期乳腺癌患者51例,分为A、B2组。A组为初次化疗者并既往未使用过蒽环类者27例,给予吡柔比星联合多西他赛治疗;B组为既往使用过蒽环类治疗失败者24例,给予多西他赛联合顺铂治疗。比较2组的临床疗效。结果 A组晚期乳腺癌患者27例,完全缓解(CR)4例,部分缓解(PR)11例,稳定(SD)7例,进展(PD)5例,总有效率为55.5%;B组24例,CR2例,PR10例,SD6例,进展6例,总有效率为50.0%,2组CR、PR、SD、PD及总有效率比较,差异均无统计学意义(P>0.05)。结论以多西他赛为主的方案治疗晚期乳腺癌有较好的临床疗效,且不良反应能耐受,值得临床推广。
出处 《临床合理用药杂志》 2010年第21期54-55,共2页 Chinese Journal of Clinical Rational Drug Use
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