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多西他赛联合顺铂治疗晚期乳腺癌30例近期疗效分析

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摘要 目的观察多西他赛联合顺铂治疗晚期乳腺癌疗效及不良反应。方法30例患者均采用多西他赛75mg/m^2,静滴1小时,第1天,化疗前一天予地塞米松10mg,连用3天;顺铂30mg/m^2,第1~3天。28天为一周期,至少应用两周期后评价疗效。结果30例患者中完全缓解(CR)1例(3.3%),部分缓解(PR)11例(36.7%),稳定(SD)14例(46.7%),进展(PD)4例(13.3%)。总有效率(CR+PR)40%。主要不良反应为骨髓抑制,胃肠道反应。结论多西他赛联合顺铂治疗晚期乳腺癌疗效确切,不良反应可以耐受,为治疗晚期乳腺癌的有效方案。
出处 《国际医药卫生导报》 2008年第4期74-75,共2页 International Medicine and Health Guidance News
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