摘要
目的：研究谷胱甘肽Ｓ－转移酶－π在鼻咽癌患者血清中的表达及意义。方法：用酶联免疫吸附法（ＥＬＩＳＡ）分别测定了３１例（实验组）鼻咽癌患者放疗前后，２５例（对照组）正常人血清谷胱甘肽Ｓ－转移酶－π的表达。结果：实验组放疗前、放疗后、放疗后１个月、放疗后３个月的血清ＧＳＴ－π的水平分别为１．０８±０．６１，０．５３±０．３４，０．３８±０．２７和０．３３±０．１５，对照组为０．３１±０．１０，实验组放疗前与对照组比较差异有显著性（Ｐ＜０．０１）。结论：提示血清ＧＳＴ－π可作为鼻咽癌患者的标志酶。
Objective:To investigate the levels of serum glutathione S transferase(GST π)in nasopharyngeal carcinoma and its significans.Methods:The levels of serum glutathione S transferase(GST π)in 31 patients with nasopharyngeal carcinoma and 25 controls were measured by enzymelinked immunosorbent assay(ELISA).Results:The results were as follows:the levels of GST in patients with NPC before and after radiation,one month and three months are 1.08±0.61,0.53±0.34,0.38±0.27,and 0.33+0.15 respectively.The level of GST π in controls is 0.31±0.10 The level of GST π in experimental group is significantly different compared with that in controls.Conclusion:The results indicate that serum GST π is a useful tumor marker in NPC.
出处
《广东医学院学报》
1999年第1期18-19,共2页
Journal of Guangdong Medical College
