摘要
为进一步阐明克山病心肌细胞损害的机理，用细胞内微电极技术分别观察了正常对照、低Ｓｅ、单纯低Ｃｒ、低Ｓｅ低Ｃｒ饲料饲养１４周后大鼠心肌细胞电生理的改变。结果表明：单纯低铬组无变化；单纯低硒组静息电位（ＲＰ），电位幅度（ＡＰＡ）降低，电位时程（ＡＰＤ５０、ＡＰＤ９０）延长；低硒并低铬组ＲＰＡＰＡ降低，ＡＰＤ５０、ＡＰＤ９０明显延长。
To elucidate the etiology of the impairment of myocardial cells in keshan disease,With intracellular microelectrode technigue,we observed the electrophysiological changes of the four groups of rats fed seperately with:normal,low se,low Cr and low Se+low Cr fodder.Compared with the control,there is no change in low Cr group;However,in low Se group,RP and APA decreased,APD 50 and APD 90 prolonged;In low Se+low Cr group,APA decreased,APD 50 and APD 90 Prolonged significantly.It suggested that Se and Cr deficiency jointly may change the electrophysiology of myocardial cells significantly.
出处
《微量元素与健康研究》
CAS
1999年第1期1-3,共3页
Studies of Trace Elements and Health
基金
山东省教委资助
关键词
硒
铬
电生理
克山病
心肌炎
Selenium Chromium Electrophysiololgy of myocardial cells
