摘要
碳纳米管(carbon nanotubes,CNTs)是一种新型纳米材料,具有特殊的纳米结构,在生物医学领域显示出诱人的潜在应用价值和前景,正逐步引起越来越多研究者的关注。功能化碳纳米管(f-CNTs)具有特殊的识别功能、很强的细胞穿透能力和较低的细胞毒性,为它在生物传感器的发展开辟了广阔的前景,同时,也使其在药物和基因运转领域中的应用成为可能。综述了近几年国内外关于碳纳米管在生物传感器、药物和基因转运领域中的应用进展,并简要探讨了其毒性。
Within the new family of nanomaterials,carbon nanotubes(CNTs) have attracted intensive interests in the field of biomedicine because of their unique nano structures.Functionalized carbon nanotubes(f-CNTs) possess unique distinguished function and strong ability to translocate through plasma membranes and low toxicity,which provide a wider prospect for the development of biosensor and make their applications in drug and gene transfer systems being possible.Towards this subject,we review the recent domestic and international research developments of the applications of carbon nanotubes in biosensor and drug/gene delivery systems,and discuss their toxicity.
出处
《功能材料与器件学报》
CAS
CSCD
北大核心
2010年第5期437-443,共7页
Journal of Functional Materials and Devices
基金
河南工程学院青年基金项目(Y09056)
关键词
碳纳米管
功能化
生物传感器
药物转运
基因转运
毒性
carbon nanotubes
functionalization
biosensor
drug delivery
gene delivery
toxicity