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东莨菪碱在治疗重型创伤性脑损伤中的临床疗效观察

Clinical effects observation of scopolamine in treatment of severe traumatic brain injury
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摘要 目的:观察东莨菪碱治疗重型创伤性脑损伤的临床疗效,探讨提高重型创伤性脑损伤临床疗效的治疗方法。方法:选择确诊为重型创伤性脑损伤患者87例,随机分为对照组与观察组,对照组42例采用常规外科治疗,观察组45例在常规外科治疗的基础上加用东莨菪碱治疗,比较两组患者治疗后动脉血氧分压(PaO2)、氧合指数(PaO2/FiO2)及术后6个月的临床疗效。结果:观察组临床疗效好于对照组,在治疗后动脉血氧分压(PaO2)、氧合指数(PaO2/FiO2)及术后6个月的临床疗效方面比较,差异有统计学意义(P<0.05)。结论:对重型创伤性脑损伤患者加用东莨菪碱治疗,可明显提高临床治疗效果,值得临床广泛推广。 Objective:To observe the clinical effects of Scopolamine in treatment of severe traumatic brain injury.Methods:Collected 87 patients with severe traumatic brain injury,they were randomly divided into control group and observer group,42 patients were divided into control group with general surgery treatment,45 patients were divided into observer group with general surgery and Scopolamine treatment,then compare PaO2,PaO2/FiO2 and the clinical effect after 6 months.Results:The observer group' s clinical effects was better than the control group' s,there was a statistical significance(P〈0.05) in PaO2,PaO2/FiO2 and the clinical effect after 6 months.Conclusion:Patients with severe traumatic brain injury are treated with scopolamine;it can increase the clinical effects obviously and should be widely promoted.
出处 《中国当代医药》 2010年第31期47-48,共2页 China Modern Medicine
关键词 东莨菪碱 重型 颅脑损伤 Scopolamine Severe Head injury
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  • 1陈华文,祝伟,李树生,郑智.重型颅脑损伤死亡危险因素的分析[J].中华急诊医学杂志,2006,15(3):216-218. 被引量:39
  • 2陶家华.预测严重脑外伤转归的诸因素[J].国外医学:神经病学.神经外科学分册,1986,13:293-293.
  • 3JENNETT B,TEASDALE G.Prognosis after Severe Head Injury[M].In:Jennett B,Teasdale G.Management of head injuries.Philadephia:Davis Co,1981.317-320.
  • 4PLETROPAOLI JA,ROGERS FB,SHACKFORD SR,et al.The Deleterious Effects of Intraoperative Hypotension on Outcome in Patients with Severe Head Injury[J].J Trauma(S1079-6061),1992,33(3):403-403.
  • 5CHESNUT RM,MARSHALL LF,KLAUBER MR,et al.The Role of Secondary Brain Injury in Determining Outcome from Severe Head Injury[J].J Trauma(S1079-6061),1993,34(2):216-216.
  • 6PIGULA FA,WALD SI,SHACKFORD SR,et al.The Effect of Hypotension and H Ypoxia on Children with Severe Head Injuries[J].J Ped Surg(S0022-3476),1993,28(3):310-310.
  • 7ARTHUR E,EUGEN F,DONALD F.Care of Injured Patients in the Field,During Transport,And in the Emergency Department[M].Multiple Organ Failure:Pathophysiology Prevention,and Therapy.New York:Springer,2000.244-244.
  • 8YOUNG B,OTT L,HOACK D,et al.Relationship between Admission Hyperglycemia and Neurologic Outcome of Severely Brain-injured Patients[J].Ann Sury(S1009-3079),1989,210:466-466.
  • 9LAM AM,WINN HR,CULLAEN BF,et al.Hyperglycemia and Neurological Outcome in Patient with Head Injury[J].J Neurosurg(S0022-3058),1991,75:545-545.
  • 10宋光太,郑秀珏.重度颅脑损伤后血糖变化与预后关系[J].急诊医学,2000,9(2):111-112. 被引量:9

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