摘要
目的了解医院药品不良反应/事件(ADR/ADE)发生)特点及一般规律,为临床合理用药提供参考。方法采用回顾性研究方法,对某医院2006年1月至2008年12月收集到的237份ADR/ADE报告表进行统计分析。结果在237例ADR/ADE报告中,大于60岁年龄组的不良反应居首位,占24.47%;抗微生物药物不良反应居首位,占56.92%;静脉滴注给药引起的ADR/ADE居首位,占75.10%;不良反应的临床表现以皮肤及其附件损害最多,占39.18%。结论 ADR/ADE监测是医院的重要工作,开展药物警戒是患者用药安全的保障。
Objective By analyzing the characteristicsand regulars of adverse drug reaction/event（ADR/ADE） occurred in one hospital,to provide reference for clinical rational drug use.Methods To adopt the reviewing analytical method to count up and analyze 237 cases ADR/ADE report,these ADR/ADE reports were received from Jan.2006 to dec.2008 by one hospital.Results Out of the 237 cases ADR/ADE reports,58 showed ADR among the over 60 year old group,amount to 24.47%.Leading the list were antibiotics（56.92%）.The clinical expression of ADR is showed mostly skin and appendix harms,amount to 39.18%.The suspected ADR cases induced by intravenous route were most common,amount to 75.10%.Conclusion ADR monitoring is an important work for medical institutions,and pharmacovigilance is conducive to patients＇ medication safety.
出处
《中国药物警戒》
2010年第11期670-673,共4页
Chinese Journal of Pharmacovigilance
