摘要
目的:探讨静脉注射丙种球蛋白对葡萄球菌烫伤样皮肤综合征的疗效。方法:回顾性分析2007年至2009年收治的葡萄球菌烫伤样皮肤综合征共49例,根据治疗方法不同分为两组,对照组20例给予抗生素治疗,治疗组29例在对照组基础上加用静脉丙种球蛋白1g/(kg·d),用一次,对两组患儿体温正常时间、皮肤红斑及疱疹停止发展时间、皮肤疱疹干燥时间、住院天数进行分析比较。结果:治疗3d后判定疗效。治疗组治愈20例,显效7例,有效2例,无效0例,总有效率90%;对照组治愈1例,显效8例,有效9例,无效2例,总有效率43%。结论:大剂量丙种球蛋白静脉注射治疗葡萄球菌烫伤样皮肤综合征疗效显著,可快速改善症状及体征,并提高治疗效果。
Objective:To investigate the intravenous injection of gamma globulin on the staphylococcal scalded skin syndrome. Methods: Retrospective analysis from 2007 to 2009 were treated staphylococcal scalded skin syndrome in 49 patients divided into two groups according to treatment, 20 patients were given antibiotic treatment group, treatment group, 29 patients in the control group based on the increase with intravenous gamma globulin 1g / (kg ? d), with one of two groups of children with normal body temperature time to stop the development of skin erythema and herpes time of skin herpes drying time, length of hospital stay were analyzed and compared. Results : 3 d after the assessment of the efficacy. Treatment group, 20 patients were cured, 7 cases were markedly effective, 2 cases 0 cases, the total effective rate was 90%; the control group were cured in 1 case, 8 cases were markedly cffective in 9 cases and ineffective in 2 cases, the total efficiency of 43%.Conclusion: : High dose intravenous gamma globulin treatment of staphylococcal scalded skin syndrome significantly to quickly improve the symptoms and signs, and improve treatment.