摘要
目的:总结移植肾血栓形成的病因、临床表现、诊断、治疗及预后。方法:回顾分析移植肾动脉血栓形成2例,静脉血栓形成1例的临床资料。结果:1例行移植肾切除术;1例肾动脉取栓术后因未能挽救移植肾功能而最终切除;1例移植肾切除后,即刻在同侧行第2次肾移植术,并取得成功。结论:外科技术失误为其最主要的原因,另外还与高龄、幼儿、女性供体,动脉粥样硬化或狭窄,缺血时间过长等有关。动脉血栓形成主要表现为突发的无尿,静脉血栓表现为少尿伴移植肾区胀痛甚至移植肾破裂。移植肾血栓多发生在移植后2d内,是早期移植肾丧失功能的重要原因。治疗手段有抗凝溶栓治疗、手术取栓及移植肾切除术。对该病预防重于治疗。
Purpose:We discussed the etiology,clinical manifestation,diagnosis, therapy and prognosis of renal graft thrombosis (RGT).Methods:3 cases of RGT(2 arterial and 1 venous) were reported.Results:2 cases underwent nephrectomy of graft, and the another one underwent renal transplantation once more.Conclusions:In addition to the both extremes of donor age, female donors, and prolonged total ischemic time, surgical technique remains the most important cause of graft thrombosis. Sudden anuresis was the main feature of arterial thrombosis, while venous thrombosis was characterized by sudden anuresis and renal graft pain even graft rupture. RGT most occurred within 2 days after renal transplantation and was the important cause of early graft losses. 1 year graft survival was less than 3%. Therapeutic management include anticoagulatic, thrombolytic therapy and surgical procedure such as removal of thrombosis and renal graft resection. Early prevention is more important than the treatment of thrombosis.
出处
《临床泌尿外科杂志》
1999年第5期201-203,共3页
Journal of Clinical Urology
关键词
肾移植
血栓形成
同种移植
Kidney transplantation Thrombosis Transplantation,homologous
