摘要
目的:评价利培酮对于难治性精神分裂症的疗效与不良反应。方法:将70例难治性精神分裂症随机分为研究组和对照组,分别给予利培酮和氯氮平治疗12周。采用PANSS量表对于疗效进行评定,采用TESS量表对于治疗中出现的不良反应进行评定。结果:利培酮组和氯氮平组对于难治性精神分裂症均有良好效果,差异无显著性。不良反应利培酮组较氯氮平组少而轻。结论:利培酮和氯氮平对于难治性精神分裂症均有良好效果,疗效相当,利培酮的不良反应少而轻,依从性好。
Objective：To evaluate the efficacy and adverse of Risperidone in treatment - teatment achizophtrnia. Methods：A total of 70 frefractory schizophrenia 70 patients were randomly assigood to the Risperidone group and the Clozapine guroup fou 12 weeks of treatment . PANSS were used tou evaluate the dffieury, TESS and some auxiliary examinations were clinical dffects. Results： There was no significant deference between two groups. The advarne effectv of Risperidone group was less and fewer than that of Clozapine group. Conclusions ： Rispendone and Clozapine are both effective for treating treatment - resistant schizophrenia . Risperidone had less and fewer adverse effects and good compliance.
出处
《中国民康医学》
2010年第21期2752-2753,共2页
Medical Journal of Chinese People’s Health
